{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T14:16:02Z","timestamp":1778422562487,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:00:00Z","timestamp":1656374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether the presence of twin\u2010anemia polycythemia sequence (TAPS) with twin\u2010to\u2010twin transfusion syndrome (TTTS) or post\u2010laser TAPS would change outcomes using different TAPS diagnostic criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>TTTS cases undergoing laser surgery between 2012 and 2020 were included. Groups included pre\u2010laser TTTS\u2010only compared to TTTS\u00a0+\u00a0TAPS, and no post\u2010laser TAPS compared to post\u2010laser TAPS. Three prenatal TAPS diagnostic criteria were used: group A: middle cerebral artery\u2010peak systolic velocity (MCA\u2010PSV)\u00a0&gt;\u00a01.5 MoM in one twin and &lt;1 MoM in the other twin, group B: inter\u2010twin MCA\u2010PSV difference &gt;1 MoM, and group C: inter\u2010twin MCA\u2010PSV difference &gt;0.5 MoM. Perinatal outcomes including survival and severe cerebral injury were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>174 laser procedures were included. TTTS\u00a0+\u00a0TAPS cases were 16 in group A, 17 in group B, and 29 in group C. Post\u2010laser TAPS cases were 11 in group A, 6 in group B, and 12 in group C. There were no differences in preoperative, operative variables and outcomes including survival and severe cerebral injury between groups using all three TAPS diagnostic criteria. The incidence of TTTS\u00a0+\u00a0TAPS was highest in group C (16.7%), then group B (9.8%), followed by group A (9.2%). The incidence of post\u2010laser TAPS was highest in group C (9%), then group A (8.3%), followed by group B (4.5%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Presence of TAPS complicating TTTS and presence of post\u2010laser TAPS do not seem to be associated with worse perinatal outcomes including postnatal\u2010ultrasound detected cerebral injury using three different TAPS criteria. Collaborative studies are needed to investigate the validity and the performance of different TAPS criteria.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6195","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T08:28:49Z","timestamp":1654849729000},"page":"985-993","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Perinatal outcomes of pregnancies with twin\u2010anemia polycythemia sequence complicating twin\u2010to\u2010twin transfusion syndrome using different twin\u2010anemia polycythemia sequence diagnostic criteria"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5611-1231","authenticated-orcid":false,"given":"Hiba J.","family":"Mustafa","sequence":"first","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine Department of Obstetrics, Gynecology and Reproductive Sciences University of Maryland School of Medicine  Baltimore Maryland 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