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We report indications and outcomes from all EXIT procedures at a tertiary obstetric unit between 1997 and 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Retrospective cohort study with data collected from maternal and neonatal medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Indications for EXIT procedures were micrognathia (<jats:italic>n<\/jats:italic>\u00a0=\u00a07), lymphatic malformations (<jats:italic>n<\/jats:italic>\u00a0=\u00a05), cervical teratomas (<jats:italic>n<\/jats:italic>\u00a0=\u00a04), goiters (<jats:italic>n<\/jats:italic>\u00a0=\u00a02), and intra\u2010oral epulis (<jats:italic>n<\/jats:italic>\u00a0=\u00a01). Infants with a fetal teratoma were delivered earliest due to 75% presenting with preterm premature rupture of membranes or preterm labor. Low birth weight was found in 75% of these neonates; they did not survive 1\u00a0year. Intubation at EXIT occurred for 58% (<jats:italic>n<\/jats:italic>\u00a0=\u00a011) of babies, and six neonates required a tracheostomy. In four cases of fetal micrognathia, the inferior facial angle (IFA) was noted to be &lt;5th centile. All but one micrognathia case had polyhydramnios. Of the total cohort, 75% of neonates were alive at 1\u00a0year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Risks for neonatal demise with EXIT include fetal teratoma, low birth weight, and prematurity. Micrognathia has become an increasingly valid indication for the procedure. The combination of polyhydramnios and IFA &lt;5% correlates well with severe airway obstruction and suggests consideration of EXIT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6230","type":"journal-article","created":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T05:10:11Z","timestamp":1662009011000},"page":"1420-1428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Changing indications and antenatal prognostic factors for ex\u2010utero intrapartum treatment procedures"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5041-0687","authenticated-orcid":false,"given":"Hugh","family":"Porter","sequence":"first","affiliation":[{"name":"Westmead Institute for Maternal and Fetal Medicine Women's and Newborn Health Westmead Hospital  Westmead New South Wales 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