{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:49:12Z","timestamp":1747151352367,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T00:00:00Z","timestamp":1673136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to examine the value of the sonographic measurements of the choroid plexus and the lateral ventricles at 11\u201314 gestational weeks in fetuses that had the diagnosis of second\u2010trimester ventriculomegaly (VM) as a clinical reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The standard axial plane used for biparietal diameter measurement from 2D stored images in the first trimester was used to calculate the ratio between the choroid plexus and lateral ventricle diameter (PDVDR), the choroid plexus and lateral ventricle length (PLVLR) and the choroid plexus and lateral ventricle area (PAVAR) in 100 normal and 15 fetuses diagnosed with second\u2010trimester VM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In fetuses with VM, the measurements of PDVDR, PLVLR and PAVAR were all significantly smaller compared to normal fetuses (<jats:italic>p<\/jats:italic>\u00a0=\u00a0&lt;\u00a00.001, &lt;0.001, &lt;0.01). Four out of seven cases with mild VM had measurements below the 5th percentile (57%). 75% of cases with moderate or severe VM had at least one measurement below the 5th percentile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Since the axial plane of the fetal head is obtained in all first\u2010trimester routine screenings, the measurements of PDVDR, PLVLR and PAVAR could easily be integrated into routine examinations for an early detection of VM.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6293","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T05:13:35Z","timestamp":1672636415000},"page":"910-918","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Presentation of ventriculomegaly at 11\u201314\u00a0weeks of gestation: An analysis of longitudinal data"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7195-5360","authenticated-orcid":false,"given":"Kathrin B.","family":"Labrosse","sequence":"first","affiliation":[{"name":"Department for Gynecological Ultrasound and Prenatal Diagnostics Women's Hospital University of Basel  Basel Switzerland"},{"name":"Department of Biomedicine University Basel  Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Buechel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Ludwig\u2010Maximilians\u2010University (LMU) Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huelya","family":"Guelmez","sequence":"additional","affiliation":[{"name":"Department for Gynecological Ultrasound and Prenatal Diagnostics Women's Hospital University of Basel  Basel 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