{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:42:02Z","timestamp":1783687322495,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the short\u2010 and long\u2010term outcome of fetuses with evidence of extension of the choroid plexus into the frontal horns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective cohort study of fetuses diagnosed with isolated choroid plexi extending into the frontal horns. Fetuses with major central nervous system anomalies were excluded. Ultrasound and fetal\/postnatal magnetic resonance imaging (MRI) were evaluated. Postnatal outcomes, including developmental assessment, were obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty nine fetuses were diagnosed with choroid plexus extension (22 unilateral and 7 bilateral). Gestational age at diagnosis was 19.3\u00a0weeks. Three cases (10.3%) presented with nonspecific extra\u2010CNS findings. At presentation, 8\/29 (28%) cases had single\/multiple choroid plexus cysts (CPC). Twenty\u2010six (89.6%) cases underwent antenatal MRI. On MRI, four cases had punctate susceptibility weighted imaging (SWI) foci suggesting trace hemosiderin and two cases had ventriculomegaly. Antenatal follow\u2010up demonstrated resolution of the choroid plexus extension in 90% (18\/20). Gestational age at delivery was 39.6\u00a0weeks. All had normal neurologic examinations within 24\u00a0h of life. Postnatal MRI studies were notable for deep venous differences in seven cases. Long\u2010term clinical outcome was assessed in 14 cases with a median follow\u2010up of 1.75\u00a0years, with normal neurodevelopment reported in 13\/14 (92.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Most fetuses with an anterior extension of the choroid plexus as the sole sonographic finding had favorable outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6344","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T13:39:16Z","timestamp":1679492356000},"page":"756-762","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Anterior extension of the choroid plexus into the frontal horns of the fetal lateral cerebral ventricles: Prenatal findings and postnatal outcome"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3016-6282","authenticated-orcid":false,"given":"Eran","family":"Ashwal","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Blaser","sequence":"additional","affiliation":[{"name":"Department of Radiology Mount Sinai Hospital University of Toronto University of Toronto  Toronto Ontario Canada"},{"name":"Department of Diagnostic Imaging Division of Neuroradiology The Hospital for Sick Children University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Leckie","sequence":"additional","affiliation":[{"name":"Department of Radiology Mount Sinai Hospital University of Toronto University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilkash","family":"Kajal","sequence":"additional","affiliation":[{"name":"Department of Radiology Mount Sinai Hospital University of Toronto University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Krishnan","sequence":"additional","affiliation":[{"name":"Department of Radiology Mount Sinai Hospital University of Toronto University of Toronto  Toronto Ontario Canada"},{"name":"Department of Diagnostic Imaging Division of Neuroradiology The Hospital for Sick Children University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Prenatal Diagnosis and Medical Genetics Program Mount Sinai Hospital University of Toronto  Toronto Ontario Canada"},{"name":"Department of Pediatrics Division of Clinical and Metabolic Genetics The Hospital for Sick Children University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maian","family":"Roifman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Prenatal Diagnosis and Medical Genetics Program Mount Sinai Hospital University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ants","family":"Toi","sequence":"additional","affiliation":[{"name":"Department of Radiology Mount Sinai Hospital University of Toronto University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Chitayat","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Prenatal Diagnosis and Medical Genetics Program Mount Sinai Hospital University of Toronto  Toronto Ontario Canada"},{"name":"Department of Pediatrics 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