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Multiple factors can contribute to the development of a cleft. We discuss the epidemiology and risk factors that increase the likelihood of having a newborn with a cleft. The purpose of this article is to review the prenatal investigations involved in the diagnosis and workup of these patients in addition to postpartum treatment, prognostic factors, and counseling families regarding future recurrence risk.<\/jats:p>","DOI":"10.1002\/pd.6418","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T13:53:43Z","timestamp":1691502823000},"page":"1310-1319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Prenatal diagnosis of cleft lip and\/or palate: What do we tell prospective parents?"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5551-4967","authenticated-orcid":false,"given":"Courtney","family":"Wilkes","sequence":"first","affiliation":[{"name":"Department of Plastic and Maxillofacial Surgery The Royal Children's Hospital  Melbourne Victoria 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