{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:51:13Z","timestamp":1791543073047,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015988","name":"Norman Beischer Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015988","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Emerging evidence supporting the use of valaciclovir to reduce fetal infection after maternal primary cytomegalovirus (CMV) infection has stimulated interest in routine CMV serological screening in pregnancy. It is important to understand the healthcare consumer perspective of a CMV infection during pregnancy to minimize unintended harms of screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a qualitative study using semi\u2010structured interviews with Australian women who had a lived experience of CMV infection following serological testing during pregnancy. Participants were recruited via social media and healthcare consumer networks, and purposively selected to capture a range of perinatal outcomes. Interview transcripts were analyzed using inductive content analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve participants were interviewed: 6 had a live birth, 4 had terminations of pregnancy, 1 had a neonatal death and 1 was pregnant at the time of interview. Four major categories emerged from the analysis. Women reported a lack of CMV awareness among themselves, their social networks, and among their health care providers. The participants described their experience as \u201chard\u201d and \u201cstressful\u201d. Uncertainty and variability characterized their clinical decision\u2010making process. The pregnancy and postpartum periods were marked by ongoing anxiety about the long\u2010term impacts of CMV. Women supported screening for CMV, decision making and reproductive choice, but acknowledged that routine testing may not be desired by everyone and may increase stress and terminations of pregnancy. Important coping strategies included obtaining support from partners, family, and other families with lived experience of CMV, as well as having access to knowledgeable and sensitive healthcare professionals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Serological diagnosis of maternal CMV infection during pregnancy can have severe and prolonged psychological impacts on parents, regardless of the pregnancy outcome. Improving healthcare professionals' knowledge and public awareness are essential before widespread serological screening can be responsibly introduced. Healthcare administrators that are considering implementing a prenatal screening program for secondary prevention of fetal CMV infection should pay attention to consumer perspectives to minimize unintended harms to women and their families.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6564","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T15:05:20Z","timestamp":1712329520000},"page":"623-634","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["\u201c<i>The anxiety coming up to every scan\u2014It destroyed me<\/i>\u201d: A qualitative study of the lived experience of cytomegalovirus infection during pregnancy"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7490-6310","authenticated-orcid":false,"given":"Tanya","family":"Tripathi","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Heidelberg Victoria Australia"},{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jotara","family":"Watson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Heidelberg Victoria Australia"},{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Skrzypek","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Heidelberg Victoria Australia"},{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanako","family":"Stump","sequence":"additional","affiliation":[{"name":"CMV Australia  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Lewis","sequence":"additional","affiliation":[{"name":"Reproductive Epidemiology Group Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-3562","authenticated-orcid":false,"given":"Lisa","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Heidelberg Victoria Australia"},{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"},{"name":"Reproductive Epidemiology Group Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"The Northern Hospital Northern Health  Epping Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.20736"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1473\u20103099(17)30143\u20103"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.05.038"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6397"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454\u2010199007000\u201000003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2022.105102"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(20)31868\u20107"},{"issue":"23","key":"e_1_2_10_9_1","first-page":"00470","article-title":"The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection, following primary maternal infection acquired periconceptionally or in the first trimester of pregnancy. An individual patient data meta\u2010analysis","volume":"0002","author":"Chatzakis C","year":"2023","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2021.100356"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5107"},{"issue":"8","key":"e_1_2_10_12_1","first-page":"484","article-title":"Trends in continuity of pregnancy in women with positive cytomegalovirus IgM during the first trimester, 2008\u20102009","volume":"19","author":"Beloosesky R","year":"2017","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.12.012"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/0167482x.2019.1658734"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijns9020030"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/acm.0000000000000388"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-013-0528-y"},{"key":"e_1_2_10_18_1","unstructured":"CMV Australia.https:\/\/www.cmv.org.au\/. 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