{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:51:58Z","timestamp":1790185918036,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"6-7","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In addition to a correct prenatal diagnosis of congenital heart disease (CHD), comprehensive parental counseling is crucial to ensure that parents are well\u2010informed about the condition of the fetus. This study aims to investigate whether there is a significant difference in the information acquired by parents through traditional counseling, utilizing 2\u2010dimensional (2D) illustrations and images, compared to an advanced approach utilizing personalized three\u2010dimensional (3D) printed models of the fetal heart developed from 3D ultrasound imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study, designed as a pilot randomized control trial, enrolled pregnant women with gestational ages greater than 18\u00a0weeks, whose fetuses were diagnosed with CHD and referred to our center between November, 2020 and June, 2021. Two groups of patients were included in the study. The first group received standard medical counseling with 2D images and illustrations, while the second group underwent advanced counseling with 3D\u2010printed patient\u2010specific heart models. Both groups were then required to complete the same survey in which the knowledge of the CHD was investigated. The 3D models were created from 3D ultrasound imaging and printed using resin materials in both 1:1 and 5:1 scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A comparison of the scores obtained from the two groups revealed that 3D visualization of the fetus's heart has the potential to increase parental knowledge about CHD and the required surgical procedures. Furthermore, all couples expressed interest in receiving a 1:1 scale model of their baby's heart.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Personalized prenatal counseling with 3D\u2010ultrasound\u2010based heart models positively impacts parents' understanding of CHD. The use of 3D models provides a more comprehensive and accessible representation of the condition, contributing to an increased knowledge gain, and potentially helping to support informed decisions regarding their child's care.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6583","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T01:54:31Z","timestamp":1716429271000},"page":"725-732","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Enhancing parental understanding of congenital heart disease through personalized prenatal counseling with 3D printed hearts"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3592-7045","authenticated-orcid":false,"given":"Francesco","family":"Galliotto","sequence":"first","affiliation":[{"name":"Pediatric Cardiac Surgery Division Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Veronese","sequence":"additional","affiliation":[{"name":"Maternal Fetal Medicine Division Department of Woman and Child Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Cerutti","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Division Department of Woman and Child Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Zemin","sequence":"additional","affiliation":[{"name":"Maternal Fetal Medicine Division Department of Woman and Child Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bertelli","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac Surgery Division Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Di Salvo","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Division Department of Woman and Child Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvise","family":"Guariento","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac Surgery Division Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimiro L.","family":"Vida","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac Surgery Division Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06801"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11936\u2010017\u20100502\u20101"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1075"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13030456"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000437597.44550.5d"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11010278"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/s1047951104001234"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5340616"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.947340"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/s1047951120001407"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26154"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.6583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,16]],"date-time":"2024-06-16T12:26:35Z","timestamp":1718540795000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.6583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":11,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/pd.6583"],"URL":"https:\/\/doi.org\/10.1002\/pd.6583","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,22]]},"assertion":[{"value":"2024-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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