{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:36:59Z","timestamp":1787585819861,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Neonatal airway compromise requiring intubation, due to micrognathia or a mass lesion obstructing the fetal airway, remains difficult but important to predict prenatally. We aimed to validate MR predictors of difficult neonatal airway (DNA) in a multicentre retrospective cohort of fetuses with micrognathia and oropharyngeal\/neck masses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The radiology databases of two large Australian maternal\u2013fetal medicine centers were searched for subjects meeting inclusion criteria: Pregnancies of &gt; 18\u00a0weeks' gestation evaluated with prenatal ultrasound and MRI between 2007 and 2022 where either fetal micrognathia or a fetal cervical, oral or oropharyngeal mass was identified on prenatal ultrasound and MRI, and details of delivery\/postnatal course were available including: nature of delivery, need for the fetal airway to be secured at delivery, degree of difficulty in airway securement, survival &gt; 24\u00a0h postnatally. Imaging predictors of a difficult neonatal airway (DNA) were assessed blinded to these neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six fetuses met the inclusion criteria. Oropharyngeal and neck mass location with polyhydramnios was 100% sensitive and 82% specific for DNA. JI\u00a0&lt;\u00a05th centile with polyhydramnios was 83% sensitive and 70% specific. JI\u00a0&lt;\u00a05th centile with polyhydramnios was associated with DNA in 80% of cases delivered by ex utero intrapartum (EXIT) delivery and none with non\u2010EXIT delivery mode.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A cervical or oropharyngeal mass with polyhydramnios predicted a difficult neonatal airway. Polyhydramnios with jaw index &lt; 5th centile was less sensitive and less specific for a difficult neonatal airway.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6651","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T03:25:11Z","timestamp":1727234711000},"page":"1593-1602","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Predicting the Difficult Neonatal Airway in Fetuses With\u00a0Micrognathia, Oropharyngeal or Neck Mass Lesions: Two\u2010Center Experience With Fetal MRI"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9668-6809","authenticated-orcid":false,"given":"Stacy","family":"Goergen","sequence":"first","affiliation":[{"name":"Monash Imaging, Monash Health  Melbourne Australia"},{"name":"School of Clinical Sciences Monash University  Melbourne 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