{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:46:59Z","timestamp":1760906819888},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2003,9,4]],"date-time":"2003-09-04T00:00:00Z","timestamp":1062633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Here we describe a foetus with intrauterine growth retardation (IUGR), cerebral malformations and a 46,XY,der(1),t(1;6)(p36.3;q25.2) karyotype owing to a familial cryptic translocation segregating in three generations. A balanced translocation was present in the mother, the maternal uncle, the aunt and the grandmother. A female first cousin with dysmorphisms, hydrocephalus and mental retardation was a carrier of a partial trisomy 1p and a partial monosomy 6q. Multiple miscarriages were present in the family pedigree. Parents of the foetus had three other pregnancies: a male with a balanced translocation, and two foetuses with 1p36.3\u2013pter monosomy and 6q25.2\u2013qter trisomy. Copyright \u00a9 2003 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.678","type":"journal-article","created":{"date-parts":[[2003,10,8]],"date-time":"2003-10-08T19:33:55Z","timestamp":1065641635000},"page":"819-823","source":"Crossref","is-referenced-by-count":9,"title":["Cryptic 1p36.3\/6q25.2 translocation in three generations ascertained through a foetus with IUGR and cerebral malformations"],"prefix":"10.1002","volume":"23","author":[{"given":"S.","family":"Cavani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Perfumo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Faravelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Malacarne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sogliani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Piombo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Zerega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zucca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Dagna Bricarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pierluigi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,9,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1993.tb03809.x"},{"issue":"3","key":"e_1_2_1_3_1","first-page":"581","article-title":"Interstitial 6q duplication in an adult male without growth delay or severe mental retardation","volume":"6","author":"Cappon SL","year":"2000","journal-title":"Med Sci Monit"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1996.tb02368.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990129)82:3<261::AID-AJMG13>3.0.CO;2-L"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0004.1999.560205.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970627)70:4<377::AID-AJMG9>3.0.CO;2-Q"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1997.tb02431.x"},{"key":"e_1_2_1_9_1","first-page":"157","volume-title":"Human Cytogenetics. 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