{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:53:52Z","timestamp":1789930432493,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe outcomes at 36\u00a0months of age in children with prenatally diagnosed Limited Dorsal Myeloschisis (LDM) and compared to Myelomeningocele (MMC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a retrospective study of all successive patients with postnatal confirmation of a prenatal diagnosis of isolated LDM who were referred to a French National Reference center from 2014 to 2023 compared with MMC cases. Postnatal evaluation at 36\u00a0months of both dysraphisms comprised standardized multidisciplinary evaluations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 245 fetuses referred with suspected MMC, 19 were prenatally diagnosed with LDM. Nine children reached 36 (\u00b1 4) months of age. All were walking. Two required clean intermittent catheterization (CIC) and three required laxatives. Sphincter functions seem to be more dysfunctional in the case of sacral LDM. None were reported to have a ventricular shunt nor having neurodevelopment impairment. The LDM children differed from the MMC children in all functions with significantly more asymptomatic children in the LDM group (LDM: 5\/9 vs. MMC: 0\/12, <jats:italic>p\u00a0&lt;<\/jats:italic>\u00a00.01), better motor (independent walking; LDM: 7\/9 vs. MMC: 2\/12; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01), urinary (need for CIC; LDM: 2\/9 vs. MMC: 10\/12; <jats:italic>p\u00a0&lt;<\/jats:italic>\u00a00.01) and cognitive (neurodevelopmental impairment; LDM: 0\/9 vs. MMC: 4\/12, <jats:italic>p\u00a0=<\/jats:italic>\u00a00.10) functions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LDM show better motor, urinary, and cognitive functions than MMC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6800","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T14:42:37Z","timestamp":1744814557000},"page":"668-675","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcome of Children With Prenatally Diagnosed Saccular Limited Dorsal Myeloschisis: The Importance of Accurate Diagnosis"],"prefix":"10.1002","volume":"45","author":[{"given":"Ana\u00efs","family":"Dugas","sequence":"first","affiliation":[{"name":"Department of Fetal Medicine DMU ORIGYNE Trousseau Hospital AP\u2010HP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4695-9519","authenticated-orcid":false,"given":"Lucie","family":"Guilbaud","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine DMU ORIGYNE Trousseau Hospital AP\u2010HP Sorbonne University  Paris 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