{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T11:32:14Z","timestamp":1773315134901,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to evaluate the current clinical practice regarding selective termination of pregnancy in dichorionic (DC) twin pregnancies in Italy to establish a national protocol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective, multicentre analysis of selective termination in DC twin pregnancies from 2010 to 2021 performed under ultrasonographic guidance using a transabdominal injection of potassium chloride via an 18\u2010 or 20\u2010gauge needle at a gestational age (GA) before fetal viability. Maternal and fetal characteristics and perinatal outcomes were collected accordingly. The primary outcome was preterm delivery before 32\u00a0weeks of gestation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 253 patients underwent selective termination at a mean GA of 17.6\u00a0weeks. Follow\u2010up information was available for 199 patients. The rates of fetal (6%) and neonatal (0.5%) deaths were low. The mean GA at delivery was 36.5\u00a0weeks (24\u201342) with 23\/199 (11.5%) preterm deliveries before 32\u00a0weeks. The only variable associated with primary outcome was GA at procedure, &gt;\u00a018\u00a0weeks (odds ratio, 2.95 [95% confidence interval 1.07\u20138.09]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the first Italian multicentre evaluation of selective termination of pregnancy in DC pregnancies. Our data suggest that the risk of preterm delivery can be reduced if the procedure is performed before 18\u00a0weeks of GA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pd.70089","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T03:50:50Z","timestamp":1769831450000},"page":"433-437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multicentre Evaluation of Perinatal Outcomes After Selective Feticide in Dichorionic Twins in Italy"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0765-1298","authenticated-orcid":false,"given":"Mariano","family":"Lanna","sequence":"first","affiliation":[{"name":"Vittore Buzzi Children's Hospital Fetal Therapy Unit \u201cU. Nicolini\u201d University of Milan  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8856-442X","authenticated-orcid":false,"given":"Daniela","family":"Casati","sequence":"additional","affiliation":[{"name":"Vittore Buzzi Children's Hospital Fetal Therapy Unit \u201cU. Nicolini\u201d University of Milan  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Fichera","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6733-7658","authenticated-orcid":false,"given":"Lucia","family":"Pasquini","sequence":"additional","affiliation":[{"name":"Department for Woman and Child Health University Hospital Careggi Fetal Therapy Unit  Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ambra","family":"Iuculano","sequence":"additional","affiliation":[{"name":"Ospedale Pediatrico Microcitemico di Cagliari  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Arduino","sequence":"additional","affiliation":[{"name":"Sant'Anna Obstetric Gynaecological Hospital Gynaecology and Obstetrics 2U A.O.U. Citt\u00e0 Della Salute e Della Scienza University of Turin  Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Verlato","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Manciucca","sequence":"additional","affiliation":[{"name":"Department for Woman and Child Health University Hospital Careggi Fetal Therapy Unit  Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana","family":"Contu","sequence":"additional","affiliation":[{"name":"Ospedale Pediatrico Microcitemico di Cagliari  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Sciarrone","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Azienda Ospedaliera Universitaria Citt\u00e0 Della Salute e Della Scienza di Torino Obstetrics \u2010 Gynaecological Ultrasound and Prenatal Diagnosis Unit  Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deab029"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.21892"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15821"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1260"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469\u20100705.1996.07060421.x"},{"key":"e_1_2_11_7_1","unstructured":"Legge 22 Maggio.1978:194 https:\/\/www.gazzettaufficiale.it\/atto\/stampa\/serie_generale\/originario."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002\u20109378(94)70083\u20104"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14249"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2022.10.028"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26126"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.22119"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2024.101363"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26170"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6286"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.11.001"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.70089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pd.70089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.70089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T17:20:36Z","timestamp":1773249636000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.70089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,30]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/pd.70089"],"URL":"https:\/\/doi.org\/10.1002\/pd.70089","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,30]]},"assertion":[{"value":"2026-01-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}