{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:30:43Z","timestamp":1791664243821,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of singleton pregnancies with anti\u2010SSA and\/or anti\u2010SSB antibodies who underwent serial fetal echocardiography between 2010 and 2022. Surveillance was weekly from 18 to 28\u00a0weeks' gestation and monthly thereafter, with mechanical PR intervals obtained by pulsed Doppler. Prolonged PR interval was defined as \u2265 140\u00a0ms on three consecutive measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 124 pregnancies met the inclusion criteria. Screening began at a median of 19.5\u00a0week gestation and continued until 34\u00a0weeks, with a median of 14 ultrasounds and 10 PR interval measurements per pregnancy. Three fetuses (2.4%) were diagnosed with heart block: two with first\u2010degree block and one with complete CHB, corresponding to one affected fetus per 359 screening ultrasounds. After dexamethasone, first\u2010degree block either normalized or remained stable. Complete CHB did not reverse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a high risk, predominantly Hispanic and non\u2010Hispanic black population, universal serial PR\u2010interval screening detected conduction abnormalities at expected rates, but only two of three cases were identified early enough for potential intervention and detection required substantial screening burden per case. These findings support the reconsideration of universal screening and suggest that risk\u2010targeted surveillance may better balance detection with screening burden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pd.70153","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T14:59:39Z","timestamp":1776783579000},"page":"1072-1078","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Yield of Serial PR Interval Screening for Fetal Heart Block in Anti\u2010SSA\/SSB Pregnancies"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2741-7952","authenticated-orcid":false,"given":"Alyssa","family":"Yeung","sequence":"first","affiliation":[{"name":"Fetal Medicine &amp; Ultrasound Division, Department of Obstetrics &amp; Gynecology and Women's Health Albert Einstein College of Medicine\/Montefiore Medical Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1736-708X","authenticated-orcid":false,"given":"Shiri","family":"Barbash Hazan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Maternal\u2010Fetal Medicine Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Vincent Center for Reproductive Biology Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8661-5608","authenticated-orcid":false,"given":"Justina","family":"Shafik","sequence":"additional","affiliation":[{"name":"Fetal Medicine &amp; Ultrasound Division, Department of Obstetrics &amp; Gynecology and Women's Health Albert Einstein College of Medicine\/Montefiore Medical Center  Bronx New York 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