{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:53:42Z","timestamp":1790909622288,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the survival outcomes of fetuses with severe left congenital diaphragmatic hernia (CDH) treated with fetal endoscopic tracheal occlusion (FETO) in Latin American centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A retrospective cohort including fetuses with isolated left CDH and severe pulmonary hypoplasia (observed\/expected lung area to head ratio (O\/E\u2010LHR) &lt;\u00a035% with liver herniation) treated with FETO in five Latin\u2010American countries was compared to a contemporary control group with similar lung size but managed expectantly during pregnancy. Propensity score matching and multivariate logistic regression were used to compare survival outcomes between cases with and without FETO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      360 fetuses with severe left CDH were included, 180 treated with FETO were compared with 180 contemporaneous cases managed expectantly during pregnancy with similar O\/E\u2010LHR values (25.2 vs. 25.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.50). FETO was performed at a mean GA of 28.4 (ranges, 24.0\u201332.0) weeks. Balloon removal was performed at a mean GA of 33.8 (ranges, 28.4\u201338.0) weeks. The mean duration of tracheal occlusion was 37.5 (ranges, 2.0\u201384.0) days. The FETO group showed significantly lower GA at delivery (35.2 vs. 37.0\u00a0weeks, respectively,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), and higher incidence of preterm prelabor rupture of membranes (47.8% vs. 20.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0&lt;\u00a00.001). The neonatal survival rate was significantly higher in the FETO group compared with the expectant care group (39.4% vs. 8.9%, respectively,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) (odds ratio: 14.8; 95% confidence interval [CI]: 7.1\u201330.9;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In Latin American centers, FETO was associated with a significant increase in survival among fetuses with left CDH and severe lung hypoplasia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pd.70175","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T18:09:27Z","timestamp":1779905367000},"page":"1251-1257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Latin American Multicenter Study of Fetal Endoscopic Tracheal Occlusion for Severe Left Diaphragmatic Hernia"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5999-866X","authenticated-orcid":false,"given":"Rogelio","family":"Cruz\u2010Mart\u00ednez","sequence":"first","affiliation":[{"name":"Fetal Medicine and Surgery Center Instituto Medicina Fetal M\u00e9xico  Guadalajara Jalisco M\u00e9xico"},{"name":"Hospital de Especialidades del Ni\u00f1o y la Mujer  Quer\u00e9taro M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savino","family":"Gil\u2010Pugliese","sequence":"additional","affiliation":[{"name":"Hospital Privado Universitario de C\u00f3rdoba  C\u00f3rdoba Argentina"},{"name":"Instituto Universitario de Ciencias Biom\u00e9dicas de C\u00f3rdoba  C\u00f3rdoba Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3642-5858","authenticated-orcid":false,"given":"Rodrigo","family":"Ruano","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine Department of Obstetrics Gynecology and Reproductive Sciences University of Miami Miller School of Medicine &amp; Jackson Memorial Hospital  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saulo","family":"Molina\u2010Giraldo","sequence":"additional","affiliation":[{"name":"Section of Fetal Therapy and Fetal Surgery Unit Division of Maternal\u2013Fetal Medicine Department of Obstetrics and Gynecology Hospital de San Jos\u00e9, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS)  Bogot\u00e1 Colombia"},{"name":"Maternal\u2013Fetal Medicine Unit Department of Gynecology and Obstetrics Faculty of Medicine Universidad Nacional de Colombia  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Azevedo Carvalho","sequence":"additional","affiliation":[{"name":"Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia Universidade de Sao Paulo, Faculdade de Medicina FMUSP  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E.","family":"Sanin\u2010Blair","sequence":"additional","affiliation":[{"name":"Servicio de Medicina Materno Fetal Universidad Pontificia Bolivariana, Cl\u00ednica Universitaria Bolivariana  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Servicio de Medicina Materno Fetal Universidad Pontificia Bolivariana, Cl\u00ednica Universitaria Bolivariana  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Gil\u2010Guevara","sequence":"additional","affiliation":[{"name":"Instituto Peruano de Medicina y Cirug\u00eda Fetal  Lima Per\u00fa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0172-1304","authenticated-orcid":false,"given":"Lucas","family":"Ota\u00f1o","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Unit, Obstetrics Service Hospital Italiano de Buenos Aires &amp; Universidad Hospital Italiano  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5686-667X","authenticated-orcid":false,"given":"C\u00e9sar","family":"Meller","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Unit, Obstetrics Service Hospital Italiano de Buenos Aires &amp; Universidad Hospital Italiano  Buenos Aires 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