{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T20:23:29Z","timestamp":1700166209812},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,12,21]],"date-time":"2004-12-21T00:00:00Z","timestamp":1103587200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2004,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Uterine contractions (UC) in twin pregnancy are often experienced, yet the effects of UC in twin\u2013twin transfusion syndrome (TTTS) remain to be clarified. The recipient heart preload condition and the effects of UC were evaluated and the final objective was to clarify the effects of tocolysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Firstly, the preload indexes (PLIs) and cardiothoracic area ratios (CTARs) were analyzed on both fetuses of 10 TTTS cases, aged from 14 to 28 gestational weeks in stage III\/IV cases for evaluating the preload condition. Then, the PLIs in the presence and absence of UC in the recipient fetuses were determined to evaluate the difference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The PLIs of the recipient and the donor fetuses were 0.78 \u00b1 0.34 (<jats:italic>n<\/jats:italic> = 163) and 0.35 \u00b1 0.13 (<jats:italic>n<\/jats:italic> = 71) respectively. The CTARs were 30.2 \u00b1 6.1 (<jats:italic>n<\/jats:italic> = 62) and 23.4 \u00b1 5.4 (<jats:italic>n<\/jats:italic> = 62) respectively. The PLIs in the absence and presence of UC in the recipient fetuses were 0.69 \u00b1 0.29 and 0.99 \u00b1 0.38 (<jats:italic>n<\/jats:italic> = 35). All above comparisons showed highly significant differences (<jats:italic>p<\/jats:italic> &lt; 0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The recipient fetuses have signs of cardiac dilatation and a high\u2010preload condition. UC transiently further raises high\u2010preload conditions of the recipient fetus. Thus, tocolysis may be necessary for management in cases of early\u2010onset severe TTTS. Copyright \u00a9 2004 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.835","type":"journal-article","created":{"date-parts":[[2004,12,21]],"date-time":"2004-12-21T15:45:23Z","timestamp":1103643923000},"page":"977-980","source":"Crossref","is-referenced-by-count":1,"title":["Uterine contractions might increase heart preload in the recipient fetus in early\u2010onset twin\u2013twin transfusion syndrome: an ultrasound assessment"],"prefix":"10.1002","volume":"24","author":[{"given":"Yuichiro","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigenori","family":"Iwagaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumiko","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Kawabata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruhiko","family":"Tamaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,12,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2001.0715"},{"key":"e_1_2_1_3_1","first-page":"119","volume-title":"Fetal Cardiac Function","author":"Chiba Y","year":"1995"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000263589"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00706.x"},{"key":"e_1_2_1_6_1","first-page":"776","article-title":"Changes in the umbilical venous blood flow of human fetus in labor","volume":"37","author":"Murakami M","year":"1985","journal-title":"Nippon Sanka Fujinka Gakkai Zasshi"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994586"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-1999-6817"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7200292"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.142"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02392-X"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2001.0758"},{"key":"e_1_2_1_13_1","first-page":"147","volume-title":"Proc 9th World Cong Ultrasound Obstet Gynecol (ISUOG)","author":"Utsu M","year":"1999"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.72.1.74"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.835","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.835","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T17:46:46Z","timestamp":1700156806000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12,15]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2004,12,15]]}},"alternative-id":["10.1002\/pd.835"],"URL":"https:\/\/doi.org\/10.1002\/pd.835","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12,15]]}}}