{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T09:15:41Z","timestamp":1777108541982,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2004,8,3]],"date-time":"2004-08-03T00:00:00Z","timestamp":1091491200000},"content-version":"vor","delay-in-days":33,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Fetal face malformations represent one of the most challenging prenatal diagnoses mainly because of the wide range of morphological features involved. We tested an approach based on a combination of conventional two\u2010dimensional ultrasound with the more recent three\u2010dimensional technique plus magnetic resonance imaging, in order to improve parents' understanding of fetal face anomalies, thereby facilitating parent counselling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two cases of fetal facial anomaly were studied using these combined techniques; one had severe micrognathia and malformation of the ears with preauricular tags, while the other had bilateral dacryocystocele and severe hypertelorism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The images generated by three\u2010dimensional ultrasound enabled the parents to visualize their child immediately and helped them to adjust to the diagnosis of facial defects and its clinical consequences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>An approach based on combined use of different imaging techniques was found useful in both cases. Copyright \u00a9 2004 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.925","type":"journal-article","created":{"date-parts":[[2004,8,3]],"date-time":"2004-08-03T15:44:13Z","timestamp":1091547853000},"page":"508-512","source":"Crossref","is-referenced-by-count":7,"title":["The role of integrated imaging techniques for prenatal prediction of phenotype in two cases of facial anomalies"],"prefix":"10.1002","volume":"24","author":[{"given":"M. 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Ultrasound","volume":"21","author":"Mittermayer C","year":"2003","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(1999)036<0012:PTUCM>2.3.CO;2"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1991.01010012.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1995.14.5.349"},{"key":"e_1_2_1_12_1","first-page":"343","article-title":"Early prenatal MR imaging diagnosis of polymycrogyria","volume":"25","author":"Righini A","year":"2004","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_1_13_1","volume-title":"Smith's Recognizable Patterns of Human Malformation","author":"Kenneth LJ","year":"1997"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.925","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T17:32:37Z","timestamp":1700155957000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["10.1002\/pd.925"],"URL":"https:\/\/doi.org\/10.1002\/pd.925","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}