{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:15:26Z","timestamp":1792167326258,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2001,5,18]],"date-time":"2001-05-18T00:00:00Z","timestamp":990144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2001,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have evaluated the role of a rapid and radical method of amniodrainage in the treatment of severe twin\u2013twin transfusion. The outcome of 15 patients with severe twin\u2013twin transfusion for which a amniodrainage was performed by means of a vacuum bottle system was compared with the outcome of 15 patients with a similar condition, matched for gestational age at the time of the initial procedure and drained using a standard procedure. In the study group the amniodrainage ended when no amniotic fluid could be aspirated, whereas the women in the standard group were drained with a syringe system and the fluid was removed until the deepest amniotic fluid pool was &lt;8\u2009cm. At the initial procedure, the mean volume of amniotic fluid drained was significantly (<jats:italic>p<\/jats:italic>&lt;0.05) higher (3252 vs 2153\u2009ml) and the length of the procedure significantly (<jats:italic>p<\/jats:italic>&lt;0.001) shorter (21 vs 41\u2009min) in the study group than in the standard group. The mean post\u2010procedure amniotic fluid index was significantly (<jats:italic>p<\/jats:italic>&lt;0.001) smaller (2.9 vs 7.7\u2009cm) after radical amniodrainage than after the standard amniodrainage. The mean number of procedures was significantly (<jats:italic>p<\/jats:italic>&lt;0.001) lower (1.5 vs 5.6) in the study group compared to the standard group. In the study group the mean placental thickness increased significantly (<jats:italic>p<\/jats:italic>&lt;0.001) from 9\u2009mm before the procedure to 49\u2009mm after, and the overall perinatal survival rate was 80% and the proportion of pregnancies with at least one survivor was 93%. The present data indicate that early, rapid and radical amniodrainage is an effective and low\u2010cost therapy for severe twin\u2013twin transfusion syndrome. Compared to the standard amniodrainage technique it also appears to reduce the need for multiple procedures. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.96","type":"journal-article","created":{"date-parts":[[2002,9,11]],"date-time":"2002-09-11T01:23:48Z","timestamp":1031707428000},"page":"471-476","source":"Crossref","is-referenced-by-count":31,"title":["Rapid and radical amniodrainage in the treatment of severe twin\u2013twin transfusion 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