{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:05:25Z","timestamp":1753869925507,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Discovery"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aims to compare the efficiencies of three noninvasive technologies in monitoring the perioperative hemodynamics of children with congenital heart disease (CHD) including ventricular septal defects with or without atrial septal defects. Three noninvasive technologies included transthoracic echocardiography (TTE), electrical cardiometry (EC), and vasoactive inotropic score (VIS). Parameters included left ventricular ejection fraction (LVEF) and cardiac index (cardiac index monitored by ultrasound, uCI) in TTE, cardiac index (cardiac index monitored by electrical cardiometry, eCI) and systemic vascular resistance index (SVRI) in EC, and VIS. Seventy\u2010four children were eligible. Three types of adverse events (AEs) related to disease activity and prognosis were observed, including cardio\u2010pulmonary resuscitation in five cases (5\/74, 6.76%), hypoxic\u2010ischemic brain damage in four cases (4\/74, 5.41%) and hemopurification in four cases (4\/74, 5.41%). Except for LVEF, eight parameters (VISmax [maximum VIS], VISmea [mean VIS], uCImea [mean uCI], uCImin [minimum uCI], eCImea [mean eCI], eCImin [minimum eCI], SVRImea [mean SVRI], and SVRImin [minimum SVRI]) showed predictive value for any AE (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). VISmea, uCImea, and eCImea demonstrated the highest accuracy and linear associations (AUROC &gt; 0.9, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.00). Linear associations also existed between the three groups of parameters and the duration of mechanical ventilation (MV) and the length of stay (LOS) in the intensive care unit (ICU). The duration of MV and the LOS in the ICU increased as VISmea rose, or uCImea and eCImea fell (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). LVEF in TTE could not predict any AE (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a00.05) and not fully reflect the cardiovascular function. Therefore, most parameters obtained in TTE, EC, and VIS can reflect the perioperative hemodynamics of children with CHD, with VISmea, uCImea, and eCImea being most accurate.<\/jats:p>","DOI":"10.1002\/pdi3.2505","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T06:24:25Z","timestamp":1726208665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative hemodynamic parameters monitored by three noninvasive technologies in children with congenital heart disease: A prospective study"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-8126","authenticated-orcid":false,"given":"Xiaoyu","family":"Xiong","sequence":"first","affiliation":[{"name":"Department of Pediatric Intensive Care Unit Children's Hospital of Chongqing Medical University  Chongqing China"},{"name":"National Clinical Research Center for Child Health and Disorders  Chongqing China"},{"name":"Ministry of Education Key Laboratory of Child Development and Disorders  Chongqing China"},{"name":"China International Science and Technology Cooperation Base of Child Development and Critical Disorders  Chongqing China"},{"name":"Chongqing Key Laboratory of Pediatrics  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care Unit Children's Hospital of Chongqing Medical University  Chongqing China"},{"name":"National Clinical Research Center for Child Health and Disorders  Chongqing China"},{"name":"Ministry of Education Key Laboratory of Child Development and Disorders  Chongqing China"},{"name":"China International Science and Technology Cooperation Base of Child Development and Critical Disorders  Chongqing China"},{"name":"Chongqing Key Laboratory of Pediatrics  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care Unit Children's Hospital of Chongqing Medical University  Chongqing China"},{"name":"National Clinical Research Center for Child Health and Disorders  Chongqing China"},{"name":"Ministry of Education Key Laboratory of Child Development and Disorders  Chongqing China"},{"name":"China International Science and Technology Cooperation Base of Child Development and Critical Disorders  Chongqing China"},{"name":"Chongqing Key Laboratory of Pediatrics  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Emergency Children's Hospital of Chongqing Medical University  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7911-9167","authenticated-orcid":false,"given":"Chengjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care Unit Children's Hospital of Chongqing Medical University  Chongqing China"},{"name":"National Clinical Research Center for Child Health and Disorders  Chongqing China"},{"name":"Ministry of Education Key Laboratory of Child Development and Disorders  Chongqing China"},{"name":"China International Science and Technology Cooperation Base of Child Development and Critical Disorders  Chongqing China"},{"name":"Chongqing Key Laboratory of Pediatrics  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1273-7"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-016-0271-5"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1139-6"},{"key":"e_1_2_13_5_1","first-page":"159","article-title":"Low cardiac output syndrome in the postoperative period of cardiac surgery. 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