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Dispensing records were extracted for each pregnancy event (<jats:italic>N<\/jats:italic>\u2009=\u20091\u2009276\u2009084 dispenses).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 106\u2009074 births, 1527 ectopic pregnancies and 25\u2009180 terminations of pregnancy. Dispensed medicines were linked to 28.0% of the pregnancy events. Multiple birth pregnancies were 50% more likely to be dispensed a medicine in the first trimester. As parity increased, so did the likelihood of a medicine being dispensed in pregnancy. Women who were dispensed a medicine were twice as likely to smoke during pregnancy and were 14% more likely to have a registered birth defect. During the first trimester, medicines from category D or X of the risk of drug use in pregnancy were dispensed to 2.1% of all pregnancy events. The WHO ATC \u2018Psychoanaleptics\u2019 category was dispensed to 3.8% of all pregnancy events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Linkage of dispensing data to pregnancy events is feasible and this approach to post\u2010marketing surveillance will add to the resources available in Australia to investigate pregnancy outcomes in relation to the safe use of prescribed medicines in pregnancy. Copyright \u00a9 2009 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.1705","type":"journal-article","created":{"date-parts":[[2009,1,28]],"date-time":"2009-01-28T08:29:26Z","timestamp":1233131366000},"page":"211-225","source":"Crossref","is-referenced-by-count":47,"title":["Pharmacovigilance in pregnancy using population\u2010based linked datasets"],"prefix":"10.1002","volume":"18","author":[{"given":"Lyn","family":"Colvin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Slack\u2010Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona J.","family":"Stanley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Bower","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,28]]},"reference":[{"key":"e_1_2_1_2_2","unstructured":"World Health Organisation.Pharmacovigilance: ensuring the safe use of medicines.WHO Policy Perspectives on Medicines.2004[cited 31 October 2008]. 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