{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:24:18Z","timestamp":1765758258974},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,4,5]],"date-time":"2010-04-05T00:00:00Z","timestamp":1270425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Various data sources may be used in pharmacoepidemiological studies. When they cannot be obtained from valid databases, medical data must be obtained from physicians or patients. In the CADEUS study, both patients and their prescribers reported medical data allowing investigation of the concordance between these sources.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>CADEUS is a French national cohort study of traditional non\u2010steroidal anti\u2010inflammatory drug (NSAID) and coxib users conducted between September 2003 and August 2004 in France that employed self\u2010administered questionnaires to obtain medical data from patients and their prescribers. The Kappa statistic (<jats:italic>\u03ba<\/jats:italic>) was used to measure concordance between patients and prescribers in 18\u2009530 pairs with regard to previous medical history and index NSAID indication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For previous medical history, the proportion of agreement ranged from 70.7 to 99.2% and concordance was: <jats:italic>substantial<\/jats:italic> (<jats:italic>\u03ba<\/jats:italic>\u2009=\u20090.61\u20130.80) for hypertension, myocardial infarction, stroke and diabetes; <jats:italic>moderate<\/jats:italic> (<jats:italic>\u03ba<\/jats:italic>\u2009=\u20090.41\u20130.60) for angina pectoris, peripheral arterial disease and hypercholesterolaemia; <jats:italic>fair<\/jats:italic> (<jats:italic>\u03ba<\/jats:italic>\u2009=\u20090.21\u20130.40) for unstable angina, cardiac insufficiency, dyspepsia, gastroesophageal reflux and gastric ulcer; <jats:italic>slight<\/jats:italic> (<jats:italic>\u03ba<\/jats:italic>\u2009&lt;\u20090.21) for upper gastrointestinal haemorrhage. For index NSAID indication, the proportion of agreement ranged from 84.3 to 99.4% and concordance was <jats:italic>almost perfect<\/jats:italic> (<jats:italic>\u03ba<\/jats:italic>\u2009=\u20090.81\u20131.00) for inflammatory rheumatism, flu\u2010like symptoms, dysmenorrhoea and dental pain; <jats:italic>substantial<\/jats:italic> for arthritis, back pain and headache; <jats:italic>moderate<\/jats:italic> for osteoarticular pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Concordance was better for specific or serious conditions both regarding previous medical history and indication. Prescriber or patient perception and understanding may reduce concordance for certain items. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.1951","type":"journal-article","created":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T00:17:32Z","timestamp":1270599452000},"page":"474-481","source":"Crossref","is-referenced-by-count":20,"title":["Concordance between prescriber\u2010 and patient\u2010reported previous medical history and NSAID indication in the CADEUS cohort"],"prefix":"10.1002","volume":"19","author":[{"given":"Annie","family":"Fourrier\u2010R\u00e9glat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huynh 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