{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:10:09Z","timestamp":1761513009640},"reference-count":36,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T00:00:00Z","timestamp":1311897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Concomitant use of anti\u2010dementia drugs with psychotropic drugs is potentially problematic in patients with dementia. The aim of this study was to investigate how frequently patients in Norway use anti\u2010dementia drugs concomitantly with psychotropic drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Analyses are based on data from the Norwegian Prescription Database. All patients who had an anti\u2010dementia drug (ATC\u2010code N06D) dispensed from a Norwegian pharmacy between January 2004 and July 2009 were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 33\u2009816 individuals received anti\u2010dementia drugs at some time during this period. The total concomitant use of anti\u2010dementia drugs with psychotropic drugs was 57.4% in men and 65.8% in women. Compared with men, a significantly higher percentage of women used antidepressants (35.8% versus 27.2%), mild hypnotics (28.8% versus 23.6%), benzodiazepines (25.4% versus 20.8%) and opioids (22.8% versus 17.4%) concomitantly with anti\u2010dementia drugs. Concomitant use of antipsychotics with anti\u2010dementia drugs was about 16% for both male and female patients. Of the total sample, 11.9% of the women and 11.7% of the men used acetylcholinesterase inhibitor (AChEI) anti\u2010dementia drugs concomitantly with an interacting psychotropic drug.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The concomitant use of psychotropic drugs with anti\u2010dementia drugs was extensive, especially among women. Co\u2010medication with potentially interacting drugs occurred at a rate of one in 10. The concomitant use of anti\u2010dementia drugs with psychotropic drugs identified in this study may inform the ongoing clinical debate about drug use in this patient group. 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