{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:56:24Z","timestamp":1761947784147},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T00:00:00Z","timestamp":1332288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to understand the characteristics of drug utilisation researches (DURs) using concepts of defined daily dose in China and to provide further suggestion for future DURs in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>DURs using concepts of defined daily dose published in China were identified from China Journal Full\u2010text Database, and in\u2010depth data analysis was conducted for DURs published in every even\u2010numbered year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 2,911 DURs published between 1989 and 2009 were identified, of which 1,268 were included for further data analysis. All studies were hospital\u2010based. Types of drugs commonly assessed in DURs were Anti\u2010infectives for systemic use (34.1%), drugs for Nervous system (25.5%) and drugs for Alimentary tract and metabolism (14.3%). In addition, 63 DURs published in even\u2010numbered year focusing on Chinese Herbal Medicine (CHM) were identified. Commonly used sources of defined dose were <jats:italic>Xin Bian Yao Wu Xue\/New Materia Medica<\/jats:italic> (83.9%), drug information leaflets (66.8%) and <jats:italic>Chinese Pharmacopoeia<\/jats:italic> (52.0%). Common indicators used in DURs include defined daily doses (DDDs), drug utilisation index (DUI) and daily dose cost (DDC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DUR is a popular method to explore the use of both pharmaceutical drugs and CHM in China. The definition of defined daily dose and its related indicators presented in the DURs were highly varied. From this, it follows that DURs with more consistent methodology are highly needed for a thorough understanding of drug utilisation in China. Apart from DURs focusing on the hospital setting, more DURs from other health settings are needed. Copyright \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.3240","type":"journal-article","created":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T02:13:26Z","timestamp":1332468806000},"page":"1118-1124","source":"Crossref","is-referenced-by-count":20,"title":["Review of the use of defined daily dose concept in drug utilisation research in China"],"prefix":"10.1002","volume":"21","author":[{"given":"Lida","family":"Teng","sequence":"first","affiliation":[{"name":"Department of Drug Policy and Management, Graduate School of Pharmaceutical Sciences The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua\u2010wen","family":"Xin","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Wuhan General Hospital  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hege Salvesen","family":"Blix","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Drug Statistics Methodology Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiichiro","family":"Tsutani","sequence":"additional","affiliation":[{"name":"Department of Drug Policy and Management, Graduate School of Pharmaceutical Sciences The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,21]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Introduction to drug utilization research","author":"World Health Organization (WHO)","year":"2003"},{"key":"e_1_2_8_3_1","volume-title":"Guidelines for ATC classification and DDD assignment","author":"WHO","year":"2010"},{"key":"e_1_2_8_4_1","volume-title":"Pharmacoepidemiology and Therapeutic Risk Management","author":"Wettermark B","year":"2008"},{"key":"e_1_2_8_5_1","unstructured":"WHO Collaborating Centre for Drug Statistics Methodology.http:\/\/www.whocc.no\/(accessed 17 October 2010)."},{"issue":"3","key":"e_1_2_8_6_1","first-page":"8","article-title":"Jing Shen Yao Wu Li Yong Yan Jiu De Qing Kuang Jian Jie (Introduction of current drug utilisation studies of psychosis medication","volume":"2","author":"Ji JD","year":"1988","journal-title":"Chinese Journal of Drug Dependence"},{"issue":"2","key":"e_1_2_8_7_1","first-page":"112","article-title":"Drug utilisation research","volume":"5","author":"Cha ZL","year":"1996","journal-title":"Chinese Journal of Pharmacoepidemiology"},{"issue":"3","key":"e_1_2_8_8_1","first-page":"170","article-title":"Description tool and analysis method in drug utilisation research","volume":"6","author":"Capella D","year":"1997","journal-title":"Chinese Journal of Pharmacoepidemiology"},{"issue":"5","key":"e_1_2_8_9_1","first-page":"215","article-title":"Yi Yuan Yao Pin DDD Shu Pai Xu Fen Xi De Yuan Li Ji Li Yong (The principle and utilization of sequential analysis of DDD system of drug in hospitals)","volume":"7","author":"Zou H","year":"1996","journal-title":"Journal of China Pharmacy"},{"key":"e_1_2_8_10_1","unstructured":"Pharmacopoeia Commission of the Chinese Ministry of Public Health.The Pharmacopoeia of the People's Republic of China (in Chinese) 1985\u20132005 editions1985; 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