{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T15:58:44Z","timestamp":1781020724965,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T00:00:00Z","timestamp":1381881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prescription drug abuse is a critical problem in the USA and has been linked to more deaths than automobile accidents. Despite this growing epidemic, the USA lacks a timely early warning system. Poison centers (PCs) have the potential to act as sentinel reporting entities for prescription drug abuse and misuse due to near\u2010real\u2010time data reporting and abundant coverage in the USA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the Researched Abuse, Diversion and Addiction\u2010Related Surveillance (RADARS\u00ae) System PC program were compared with data from the Drug Abuse Warning Network (DAWN) from 2004 through 2010. Population rates of PC call mentions regarding abuse and misuse of prescription opioids were compared with population rates of emergency department visit mentions of the same using linear regression. Products included in the analysis were the following: buprenorphine, fentanyl, hydrocodone, hydromorphone, methadone, morphine, and oxycodone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The strength of association between RADARS System PC data and DAWN emergency department visits regarding all opioids in aggregate was strong (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.81, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The correlations between the two programs at the drug class level also were strong for buprenorphine, hydrocodone, hydromorphone, methadone, and oxycodone (all <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009&gt;\u20090.70, all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), significant for fentanyl (<jats:italic>p<\/jats:italic>\u2009=\u20090.05), and moderate for morphine (<jats:italic>p<\/jats:italic>\u2009=\u20090.09).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Data on prescription opioid drug abuse from the RADARS System PC program correlates well with emergency room data from DAWN. Due to timeliness of data, geographic coverage and strong associations with other warning systems, PC data can be used for sentinel reporting on prescription drug abuse and misuse in the USA. Copyright \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.3533","type":"journal-article","created":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T09:46:49Z","timestamp":1381916809000},"page":"18-25","source":"Crossref","is-referenced-by-count":32,"title":["Using poison center exposure calls to predict prescription opioid abuse and misuse\u2010related emergency department visits"],"prefix":"10.1002","volume":"23","author":[{"given":"Jonathan M.","family":"Davis","sequence":"first","affiliation":[{"name":"Rocky Mountain Poison and Drug Center Denver Health and Hospital Authority  Denver CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevan G.","family":"Severtson","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center Denver Health and Hospital Authority  Denver CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Becki","family":"Bucher\u2010Bartelson","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center Denver Health and Hospital Authority  Denver CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Dart","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center Denver Health and Hospital Authority  Denver CO USA"},{"name":"Department of Emergency Medicine University of Colorado Denver  CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,16]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"The DAWN Report:Highlights of the 2010 Drug Abuse Warning Network (DAWN) Findings on Drug\u2010Related Emergency Department Visits","author":"Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality","year":"2012"},{"key":"e_1_2_8_3_1","unstructured":"M Warner LH Chen DM Makuc 2009 National Center for Health Statistics Hayattsville MD"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ajp.0000210915.80417.cf"},{"issue":"38","key":"e_1_2_8_5_1","first-page":"3","article-title":"DAWN report for 2011 will be the last; transition to CDC","volume":"24","author":"Knopf A","year":"2012","journal-title":"Alcohol Drug Abuse Wkly"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650600981137"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1901"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1P064b"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2011.587819"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1P064"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041181"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1780"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00259.x"},{"key":"e_1_2_8_14_1","unstructured":"Available at:http:\/\/www.radars.org\/. 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