{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:09:13Z","timestamp":1790762953826,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":518,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007152","name":"Vivus, Inc.","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007152","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiol Drug Saf"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1002\/pds.3612","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T19:15:06Z","timestamp":1396379706000},"page":"1017-1025","source":"Crossref","is-referenced-by-count":73,"title":["Topiramate use in pregnancy and the birth prevalence of oral clefts"],"prefix":"10.1002","volume":"23","author":[{"given":"Daniel","family":"Mines","sequence":"first","affiliation":[{"name":"HealthCore, Inc.; Wilmington DE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Tennis","sequence":"additional","affiliation":[{"name":"RTI Health Solutions; Research Triangle Park NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suellen M.","family":"Curkendall","sequence":"additional","affiliation":[{"name":"Truven Health Analytics; Cambridge MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De-Kun","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Foundation Research Institute; Kaiser Permanente; Oakland CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Peterson","sequence":"additional","affiliation":[{"name":"Vivus, Inc.; Mountain View CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth B.","family":"Andrews","sequence":"additional","affiliation":[{"name":"RTI Health Solutions; Research Triangle Park NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Calingaert","sequence":"additional","affiliation":[{"name":"RTI Health Solutions; Research Triangle Park NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Foundation Research Institute; Kaiser Permanente; Oakland CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Deshpande","sequence":"additional","affiliation":[{"name":"HealthCore, Inc.; Wilmington DE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daina B.","family":"Esposito","sequence":"additional","affiliation":[{"name":"HealthCore, Inc.; Wilmington DE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Everage","sequence":"additional","affiliation":[{"name":"Epidemiology; OptumInsight; Waltham MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal N.","family":"Holick","sequence":"additional","affiliation":[{"name":"HealthCore, Inc.; Wilmington DE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Truven Health Analytics; Cambridge MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella T.","family":"Nkhoma","sequence":"additional","affiliation":[{"name":"HealthCore, Inc.; Wilmington DE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry","family":"Quinn","sequence":"additional","affiliation":[{"name":"Epidemiology; OptumInsight; Waltham MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Rothman","sequence":"additional","affiliation":[{"name":"RTI Health Solutions; Research Triangle Park NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Arnold","family":"Chan","sequence":"additional","affiliation":[{"name":"Epidemiology; OptumInsight; Waltham MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,1]]},"reference":[{"key":"10.1002\/pds.3612-BIB0001|pds3612-cit-0001","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00004850-200109000-00008","article-title":"Topiramate as a mood stabilizer","volume":"16","author":"Letmaier","year":"2001","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1002\/pds.3612-BIB0002|pds3612-cit-0002","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/00002508-200301000-00008","article-title":"The rationale and use of topiramate for treating neuropathic pain","volume":"19","author":"Chong","year":"2003","journal-title":"Clin J Pain"},{"key":"10.1002\/pds.3612-BIB0003|pds3612-cit-0003","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/oby.2003.102","article-title":"A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity","volume":"11","author":"Bray","year":"2003","journal-title":"Obes Res"},{"key":"10.1002\/pds.3612-BIB0004|pds3612-cit-0004","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1038\/oby.2004.206","article-title":"Topiramate: long-term maintenance of weight loss induced by a low-calorie diet in obese subjects","volume":"12","author":"Astrup","year":"2004","journal-title":"Obes Res"},{"key":"10.1002\/pds.3612-BIB0005|pds3612-cit-0005","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00228-006-0220-1","article-title":"The effect of topiramate on energy balance in obese men: a 6-month double-blind randomized placebo-controlled study with a 6-month open-label extension","volume":"63","author":"Tremblay","year":"2007","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1002\/pds.3612-BIB0006|pds3612-cit-0006","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1212\/01.wnl.0000318293.28278.33","article-title":"Topiramate in pregnancy: preliminary experience from the UK epilepsy and pregnancy register","volume":"71","author":"Hunt","year":"2008","journal-title":"Neurology"},{"issue":"21","key":"10.1002\/pds.3612-BIB0007|pds3612-cit-0007","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1212\/WNL.0b013e3182574f39","article-title":"Comparative safety of antiepileptic drugs during pregnancy","volume":"78","author":"Hernandez-Diaz","year":"2012","journal-title":"Neurology"},{"key":"10.1002\/pds.3612-BIB0008|pds3612-cit-0008","unstructured":"FDA Drug Safety Communication: risk of oral clefts in children born to mothers taking Topamax (topiramate)"},{"key":"10.1002\/pds.3612-BIB0009|pds3612-cit-0009","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1002\/pds.1463","article-title":"Paroxetine in the first trimester and the prevalence of congenital malformations","volume":"16","author":"Cole","year":"2007","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1002\/pds.3612-BIB0010|pds3612-cit-0010","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/pds.1296","article-title":"Bupropion in pregnancy and the prevalence of congenital malformations","volume":"16","author":"Cole","year":"2007","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1002\/pds.3612-BIB0011|pds3612-cit-0011","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1001\/jama.2010.410","article-title":"Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death","volume":"303","author":"Patorno","year":"2010","journal-title":"JAMA"},{"key":"10.1002\/pds.3612-BIB0012|pds3612-cit-0012","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1161\/CIRCOUTCOMES.109.911461","article-title":"Risk of cardiovascular events and all-cause mortality in patients treated with thiazolidinediones in a managed-care population","volume":"3","author":"Wertz","year":"2010","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1002\/pds.3612-BIB0013|pds3612-cit-0013","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1177\/003335490912400315","article-title":"Children with orofacial clefts: health-care use and costs among a privately insured population","volume":"124","author":"Boulet","year":"2009","journal-title":"Public Health Rep"},{"key":"10.1002\/pds.3612-BIB0014|pds3612-cit-0014","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.d5931","article-title":"Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: a retrospective cohort study","volume":"343","author":"Li","year":"2011","journal-title":"BMJ"},{"key":"10.1002\/pds.3612-BIB0015|pds3612-cit-0015","first-page":"253","article-title":"TORCH infections. Toxoplasmosis, other (syphilis, varicella-zoster, parvovirus B19), rubella, cytomegalovirus (CMV), and herpes infections","volume":"2","author":"Stegmann","year":"2002","journal-title":"Curr Womens Health Rep"},{"key":"10.1002\/pds.3612-BIB0016|pds3612-cit-0016","first-page":"1","article-title":"Births: final data for 2007","volume":"58","author":"Martin","year":"2010","journal-title":"Natl Vital Stat Rep"},{"key":"10.1002\/pds.3612-BIB0017|pds3612-cit-0017","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/bdra.20735","article-title":"Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006","volume":"88","author":"Parker","year":"2010","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"issue":"5","key":"10.1002\/pds.3612-BIB0018|pds3612-cit-0018","doi-asserted-by":"crossref","first-page":"405.e1","DOI":"10.1016\/j.ajog.2012.07.008","article-title":"Use of topiramate in pregnancy and risk of oral clefts","volume":"207","author":"Margulis","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"10.1002\/pds.3612-BIB0019|pds3612-cit-0019","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1111\/j.1526-4610.2012.02190.x","article-title":"Utilization of topiramate during pregnancy and risk of birth defects","volume":"52","author":"Green","year":"2012","journal-title":"Headache"},{"key":"10.1002\/pds.3612-BIB0020|pds3612-cit-0020","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1542\/peds.111.S1.1152","article-title":"Maternal obesity and risk for birth defects","volume":"111","author":"Watkins","year":"2003","journal-title":"Pediatrics"},{"key":"10.1002\/pds.3612-BIB0021|pds3612-cit-0021","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1597\/02-142.1","article-title":"Smoking and orofacial clefts: a United Kingdom-based case-control study","volume":"41","author":"Little","year":"2004","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1002\/pds.3612-BIB0022|pds3612-cit-0022","first-page":"213","article-title":"Tobacco smoking and oral clefts: a meta-analysis","volume":"82","author":"Little","year":"2004","journal-title":"Bull World Health Organ"},{"key":"10.1002\/pds.3612-BIB0023|pds3612-cit-0023","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.drugalcdep.2011.03.010","article-title":"Predictors of persistent nicotine dependence among adults in the United States","volume":"118","author":"Goodwin","year":"2011","journal-title":"Drug Alcohol Depend"},{"key":"10.1002\/pds.3612-BIB0024|pds3612-cit-0024","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1111\/j.1360-0443.2010.02902.x","article-title":"Mental disorders as risk factors for substance use, abuse and dependence: results from the 10-year follow-up of the National Comorbidity Survey","volume":"105","author":"Swendsen","year":"2010","journal-title":"Addiction"}],"container-title":["Pharmacoepidemiology and Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpds.3612","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/pds.3612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T15:18:47Z","timestamp":1648739927000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pds.3612"}},"subtitle":["TOPIRAMATE AND ORAL CLEFTS"],"short-title":[],"issued":{"date-parts":[[2014,4,1]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"URL":"https:\/\/doi.org\/10.1002\/pds.3612","relation":{},"ISSN":["1053-8569"],"issn-type":[{"value":"1053-8569","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4,1]]}}}