{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:42:51Z","timestamp":1762004571970,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T00:00:00Z","timestamp":1395187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004417","name":"Global Fund to Fight AIDS, Tuberculosis and Malaria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004417","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to identify antibiotic prescription patterns for community\u2010acquired pneumonia (CAP) in Vietnam.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records for CAP adult patients admitted to 10 hospitals across the country were randomly selected from admission lists during the peak pneumonia season. CAP cases were identified from manual record reviews by clinical pharmacists. Data was collected using a standard data collection tool including patient clinical features on admission, comorbidities, microbiological culture results, and antibiotic regimens. Pneumonia severity was estimated using the CURB\u201065 score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 649 medical records for adult patients (55.2% male and 52.3% urban residents, median age 68\u2009years) met the selection criteria for CAP. Pneumonia severity was assessed as mild (64.1% of patients), moderate (23.0%), and severe (9.2%). Antibiotics were most frequently administered intravenously (93.4%) and as combination therapy (dual therapy 54.4%, monotherapy 42.5%, and triple therapy 3.1% of patients) regardless of CAP severity. Third\u2010generation cephalosporins were used most frequently (29.3% as monotherapy and 40.4% as combination therapy). Third\u2010generation cephalosporins were most commonly combined with penicillins and\/or quinolones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This first nationwide study provides a baseline profile of antibiotic use in the treatment of CAP. Third\u2010generation cephalosporins were widely used for initial empirical management of CAP, often in combination with quinolones, regardless of CAP severity. The study will assist in providing an evidence base to inform new national antibiotic guidelines for CAP management and will contribute locally relevant data for the national master plan addressing antibiotic resistance and the development of educational interventions to improve CAP management. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.3614","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T03:11:18Z","timestamp":1395285078000},"page":"129-136","source":"Crossref","is-referenced-by-count":6,"title":["Antibiotic therapy for inpatients with community\u2010acquired pneumonia in a developing country"],"prefix":"10.1002","volume":"24","author":[{"given":"Hieu T.","family":"Trinh","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phuong H.","family":"Hoang","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magnolia","family":"Cardona\u2010Morrell","sequence":"additional","affiliation":[{"name":"NPS MedicineWise (NPS)  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinh Hoa","family":"Vu","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phuong T. X.","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thao T. B.","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Son T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Van T. T.","family":"Pham","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Moss","sequence":"additional","affiliation":[{"name":"NPS MedicineWise (NPS)  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Dinh","sequence":"additional","affiliation":[{"name":"NPS MedicineWise (NPS)  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Dartnell","sequence":"additional","affiliation":[{"name":"NPS MedicineWise (NPS)  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huong T. L.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy Hanoi University of Pharmacy  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,19]]},"reference":[{"volume-title":"The World Medicines Situation 2011 \u2010 Rational Use of Medicines","year":"2011","author":"WHO","key":"e_1_2_9_2_1"},{"key":"e_1_2_9_3_1","unstructured":"http:\/\/www.cimsi.org.vn\/THONGKE.aspx?action=thongke&lang=vi."},{"key":"e_1_2_9_4_1","unstructured":"World Health Organisation.World Health Organisation Global Strategy for Containment of Antimicrobial Resistance.2001[cited 2013 May]; Available from:http:\/\/www.who.int\/csr\/resources\/publications\/drugresist\/WHO_CDS_CSR_DRS_2001_2_EN\/en\/."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181de0c26"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05658-11"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1003.030252"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02725.x"},{"key":"e_1_2_9_9_1","first-page":"6","article-title":"Antibiotic resistance rate of S. pneumoniae and H. influenzae in respiratory infection patients: a result from a multi\u2010central study in Vietnam (SOAR) 2010\u20132011","volume":"855","author":"Van PH","year":"2012","journal-title":"Vietnamese J Pract Med"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.12.0295"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2011.07.015"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200405-644ST"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1086\/653053"},{"issue":"3","key":"e_1_2_9_14_1","first-page":"121434","article-title":"BTS guidelines for the management of community acquired pneumonia in adults: update 2009","volume":"64","author":"Lim WS","year":"2009","journal-title":"Thorax"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.7.at1010"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1086\/382690"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2009.02239.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1086\/587666"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/511159"}],"container-title":["Pharmacoepidemiology and Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpds.3614","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpds.3614","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pds.3614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T11:31:35Z","timestamp":1696505495000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pds.3614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,19]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1002\/pds.3614"],"URL":"https:\/\/doi.org\/10.1002\/pds.3614","archive":["Portico"],"relation":{},"ISSN":["1053-8569","1099-1557"],"issn-type":[{"type":"print","value":"1053-8569"},{"type":"electronic","value":"1099-1557"}],"subject":[],"published":{"date-parts":[[2014,3,19]]}}}