{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:57:47Z","timestamp":1767826667847,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T00:00:00Z","timestamp":1522022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"UK-China Strategic Prosperity Fund","award":["PPY CHN 1590\/15SS19"],"award-info":[{"award-number":["PPY CHN 1590\/15SS19"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine antibiotic\u2010related knowledge and behaviors in rural Anhui, identify factors associated with knowledge, and explore the relationship between knowledge and antibiotic use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cross\u2010sectional study of a random sample of 2760 residents of rural China using structured interviews.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The response rate was 94.6%. A total of 2390 respondents (91.6%) believed that antibiotics can control viruses; 2007 (77.5%) respondents thought that a combination of antibiotics is more effective than a single class; and 590 (22.6%) were able to name at least one disbenefit of using antibiotics. Multivariate analysis revealed those with a higher educational level and younger age group had greater knowledge of antibiotics (OR 2.54 and 0.77, respectively). Self\u2010medication was common with 1052 (out of 2274 responses, 46.3%) of participants use over the counter or leftover medicines for common infections. Greater knowledge was associated with buying drugs without prescription (aOR 2.02; 95% CI, 1.29\u20133.17) and using leftover medication (aOR 2.80; 95% CI, 1.55\u20135.06).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Knowledge about antibiotics was low and reported use high. Worryingly those with greater knowledge had less desirable behaviors that highlights the urgent need for multifaceted interventions to change behavior.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.4429","type":"journal-article","created":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T01:54:51Z","timestamp":1522115691000},"page":"652-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Knowledge and behaviors in relation to antibiotic use among rural residents in Anhui, China"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6364-0206","authenticated-orcid":false,"given":"Jing","family":"Cheng","sequence":"first","affiliation":[{"name":"School of Public Health Anhui Medical University  Hefei Anhui China"},{"name":"School of Health Services Management Anhui Medical University  Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Coope","sequence":"additional","affiliation":[{"name":"NIHR Health Protection Research Unit in Evaluation of Interventions, School of Social and Community Medicine University of Bristol  Bristol UK"},{"name":"Public Health England  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Chai","sequence":"additional","affiliation":[{"name":"School of Public Health Anhui Medical University  Hefei Anhui China"},{"name":"School of Health Services Management Anhui Medical University  Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Oliver","sequence":"additional","affiliation":[{"name":"NIHR Health Protection Research Unit in Evaluation of Interventions, School of Social and Community Medicine University of Bristol  Bristol UK"},{"name":"Public Health England  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Kessel","sequence":"additional","affiliation":[{"name":"London School of Hygiene &amp; Tropical Medicine  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debin","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Health Services Management Anhui Medical University  Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehuan","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Public Health Anhui Medical University  Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,26]]},"reference":[{"issue":"10","key":"e_1_2_10_2_1","first-page":"688","article-title":"Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta\u2010analysis","volume":"340","author":"Costelloe C","year":"2010","journal-title":"BMJ"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0804.010312"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17907-0"},{"key":"e_1_2_10_5_1","unstructured":"O'NeillJ.Antimicrobial resistance: tackling a crisis for the health and wealth of nations.2014."},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt223"},{"key":"e_1_2_10_7_1","unstructured":"OMS.Using indicators to measure country pharmaceutical situations: fact book on WHO level one and level two monitoring indicators.2006."},{"issue":"10","key":"e_1_2_10_8_1","first-page":"849","article-title":"Antibiotic use for outpatients with common cold in Beijing","volume":"34","author":"Zhen JC","year":"2014","journal-title":"Chinese J Pharm"},{"key":"e_1_2_10_9_1","volume-title":"Study on drug use in rural area, Shandong province and Ningxia Autonomous Region","author":"Yin J","year":"2009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn054"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(95)00387-8"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl558"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq104"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084177"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2012.29217"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2929.2005.02230.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(01)00085-5"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70054-8"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(99)00304-4"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-112"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041314"},{"issue":"524","key":"e_1_2_10_22_1","first-page":"183","article-title":"Antibiotic prescribing for acute cough: the effect of perceived patient demand","volume":"56","author":"Samuel Coenen BM","year":"2006","journal-title":"Brit J R Coll Gen Pract"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(03)00231-4"},{"key":"e_1_2_10_24_1","article-title":"Management of clinical application of antibacterial","author":"Commission NHaFP","year":"2012","journal-title":"Drugs"},{"issue":"10","key":"e_1_2_10_25_1","first-page":"1260","article-title":"Comprehensive interventional management of antibacterials","volume":"17","author":"Chen W","year":"2007","journal-title":"Chinese Journal of Nosocomiology"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmu001"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40360-015-0009-x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.5214"},{"key":"e_1_2_10_29_1","unstructured":"National Bureau of Statistics of the People's Republic of China.Monitoring report of migrant workers in China 2014.http:\/\/www.stats.gov.cn\/tjsj\/zxfb\/201504\/t20150429_797821.html(accessed October 26 2017)"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1479"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm161"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-007-7214-5"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2010.01610.x"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.120568"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/48.3.435"},{"key":"e_1_2_10_36_1","unstructured":"China Food and Drug Administration.Provisions for Supervision of Drug Distribution.2007;http:\/\/eng.sfda.gov.cn\/WS03\/CL0768\/61650.html(accessed October 26 2017)"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(02)00272-8"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-6-42"}],"container-title":["Pharmacoepidemiology and Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpds.4429","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pds.4429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T16:18:08Z","timestamp":1695485888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pds.4429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,26]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1002\/pds.4429"],"URL":"https:\/\/doi.org\/10.1002\/pds.4429","archive":["Portico"],"relation":{},"ISSN":["1053-8569","1099-1557"],"issn-type":[{"value":"1053-8569","type":"print"},{"value":"1099-1557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,26]]},"assertion":[{"value":"2017-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}