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The development cohort consisted of 350 participants who completed research spirometry in the Examinations of HIV Associated Lung Emphysema (EXHALE) study, a pulmonary substudy of the Veterans Aging Cohort Study. Results were externally validated in 294 PLWH who performed spirometry for clinical indications from the University of Washington (UW) site of the Centers for AIDS Research Network of Integrated Clinical Systems cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ICD\u20109 codes performed similarly by HIV status, but alone were poor at discriminating cases from non\u2010cases of COPD when compared with spirometry (AUC 0.633 in EXHALE; 0.651 in the UW cohort). However, algorithms that combined ICD\u20109 codes with other clinical variables available in the EHR\u2014age, smoking, and COPD inhalers\u2014improved discrimination and performed similarly in EXHALE (AUC 0.771) and UW (AUC 0.734).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These data support that EHR data in combination with ICD\u20109 codes have moderately good accuracy to identify COPD when spirometry data are not available, and perform similarly in PLWH and uninfected individuals.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.4567","type":"journal-article","created":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T07:31:54Z","timestamp":1529479914000},"page":"140-147","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9702-0371","authenticated-orcid":false,"given":"Kristina","family":"Crothers","sequence":"first","affiliation":[{"name":"Department of Medicine University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla V.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington  Seattle WA USA"},{"name":"Mid\u2010Atlantic Permanente Research Institute Kaiser Permanente Mid\u2010Atlantic States  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin M.","family":"Nance","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Akgun","sequence":"additional","affiliation":[{"name":"Department of Medicine Veterans Affairs (VA) Connecticut Healthcare System and Yale University  West Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahida","family":"Shahrir","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medicine James J. 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