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However, current data on the care of refugees and migrants in initial reception centers is pending. This article provides data on prescription frequencies of various antibiotics and associated diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective observational study, patient data of 3255 patients with 6376 medical contacts in two initial reception centers in Germany were analyzed. Patient data, collected by chart review, included sociodemographic characteristics, diagnoses, and prescriptions. Antibiotic prescription behavior and corresponding physician\u2010coded diagnoses were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen percent of all patients in our study received systemic antibiotics during the observation period, with children below the age of 10\u2009years receiving antibiotics most frequently (24%). The most commonly prescribed antibiotics were penicillins (65%), macrolides (12%), and cephalosporins (7%). The most frequent diagnoses associated with antibiotic prescription were acute tonsillitis (26%), bronchitis (21%), infections of the upper respiratory tract (14%), and urinary tract infections (10%). In case of acute bronchitis 74% of the antibiotic prescriptions were probably not indicated. In addition, we found a significant number of inappropriate prescriptions such as amoxicillin for tonsillitis (67%), and ciprofloxacin and cotrimoxazol for urinary tract infections (49%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Regarding inappropriate prescription of antibiotics in refugee healthcare, this study shows a rate ranging from 8% for upper respiratory tract infections to 75% for acute bronchitis. Unnecessary use of antibiotics is a global problem contributing to gratuitous costs, side effects, and antimicrobial resistance. This research contributes to the development of stringent antibiotic stewardship regiments in the particularly vulnerable population of migrants and refugees.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.5254","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T21:37:18Z","timestamp":1619127438000},"page":"1074-1083","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prescription of antibiotics in the medical care of newly arrived refugees and migrants"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8951-9874","authenticated-orcid":false,"given":"Evelyn","family":"Kleinert","sequence":"first","affiliation":[{"name":"Department of General Practice University Medical Center G\u00f6ttingen\/Georg\u2010August\u2010University  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nele","family":"Hillermann","sequence":"additional","affiliation":[{"name":"Department of General Practice University Medical Center G\u00f6ttingen\/Georg\u2010August\u2010University  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Jablonka","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology Hannover Medical School  Hannover Germany"},{"name":"German Center for Infection Research, partner site Hanover\u2010Braunschweig  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Happle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Neonatology, and Allergology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of General Practice University Medical Center G\u00f6ttingen\/Georg\u2010August\u2010University  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Simmenroth","sequence":"additional","affiliation":[{"name":"Department of General Practice University Medical Center W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Global Trends: Forced Displacement in 2018","author":"The UN Refugee Agency","year":"2019"},{"key":"e_1_2_10_3_1","volume-title":"Das Bundesamt in Zahlen","year":"2018"},{"issue":"11","key":"e_1_2_10_4_1","first-page":"461","article-title":"Einsatz von Videodolmetschen in der ambulanten Versorgung in Hamburg \u2013 eine Bedarfsanalyse","volume":"93","author":"Mews C","year":"2017","journal-title":"Z Allg Med."},{"key":"e_1_2_10_5_1","first-page":"e8","article-title":"Erkrankungen bei Fl\u00fcchtlingen und Asylbewerbern: Daten von drei verschiedenen medizinischen Einrichtungen im Raum M\u00fcnchen aus den Jahren 2014 und 2015","volume":"141","author":"Alberer M","year":"2016","journal-title":"Dtsch Med Wochenschr."},{"key":"e_1_2_10_6_1","first-page":"1","article-title":"Does refugee status matter? 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