{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T12:20:01Z","timestamp":1700396401580},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2001,10,26]],"date-time":"2001-10-26T00:00:00Z","timestamp":1004054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To describe the process of obtaining access to the administrative health care utilization data of the Canadian province of Saskatchewan and the ethical issues involved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The report focuses on the process of obtaining data for two recent studies. In the first, associations between aplastic anemia and agranulocytosis and prior drug use were evaluated, while the second is an examination of anti\u2010arrhythmia drug utilization. In these studies, data from files containing computerized information on prescription drug use, hospitalizations, physician services and cancer registrations were linked together and also with information from hospital charts, physician records and death registrations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data on individual patients are available from the Saskatchewan datafiles after the removal of identifying variables, and access to external information from hospitals, physicians, death registrations and the patients themselves is possible. However, researchers must accept that data considered to be only indirectly relevant to the objectives of the study or which, due to small numbers, may potentially identify either patients or physicians will only be released in aggregate form.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Access to the Saskatchewan datafiles and to external information from hospitals, physicians and death registrations is normally straightforward. Restrictions that are applied are discussed. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.632","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:13:41Z","timestamp":1030317221000},"page":"607-612","source":"Crossref","is-referenced-by-count":2,"title":["Ethical issues in pharmacoepidemiologic research using Saskatchewan administrative health care utilization data"],"prefix":"10.1002","volume":"10","author":[{"given":"Nigel S. B.","family":"Rawson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,10,26]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Tri\u2010Council Policy Statement: Ethical Conduct for Research Involving Humans","year":"1998"},{"key":"e_1_2_1_3_2","first-page":"175","article-title":"Saskatchewan Health's linkable data bases and pharmacoepidemiology","volume":"6","author":"Malcolm E","year":"1993","journal-title":"Post Market Surveill"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/0470842555.ch20"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(88)90007-8"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199202203260801"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03259595"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/106002809502907-804"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1557(199701)6:1<1::AID-PDS247>3.0.CO;2-7"},{"key":"e_1_2_1_10_2","first-page":"241","article-title":"Prescription\u2010episodes to study drug utilization with the Saskatchewan Drug Plan datafile","volume":"15","author":"Rawson NSB","year":"1998","journal-title":"J Soc Admin Pharm"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00072-9"},{"key":"e_1_2_1_12_2","first-page":"159","article-title":"Acute adverse event signalling scheme using the Saskatchewan administrative health care utilization datafiles: results for two benzodiazepines","volume":"6","author":"Rawson NSB","year":"1999","journal-title":"Can J Clin Pharmacol"},{"key":"e_1_2_1_13_2","volume-title":"Manual of the International Statistical Classification of Diseases, Injuries and Causes of Death","year":"1977"},{"key":"e_1_2_1_14_2","unstructured":"RawsonNSB MalcolmE.Validity of the Recording of Cholecystectomy and Hysterectomy in the Saskatchewan Health Care Datafiles. 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