{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:18:59Z","timestamp":1792441139983,"version":"4.5.0"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U24\u2010AA020794"],"award-info":[{"award-number":["U24\u2010AA020794"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U01\u2010AA020790"],"award-info":[{"award-number":["U01\u2010AA020790"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U01\u2010AA020795"],"award-info":[{"award-number":["U01\u2010AA020795"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U01\u2010AA020799"],"award-info":[{"award-number":["U01\u2010AA020799"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U10 AA013566"],"award-info":[{"award-number":["U10 AA013566"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Accurate identification of hepatic decompensation is essential for pharmacoepidemiologic research among patients with chronic liver disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An algorithm using \u2265\u20091 inpatient or \u2265\u20092 outpatient International Classification of Diseases, 10th revision (ICD\u201010) codes for hepatic decompensation was developed in Veterans Health Administration data from October 2015 through July 2019. Medical records were reviewed by hepatologists to confirm cases. The positive predictive value (PPV) of the coding algorithm for confirmed hepatic decompensation was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hepatic decompensation was confirmed in 149\/185 records meeting the algorithm (PPV 81%; 95% CI, 70%, 90%). The most common hepatic decompensation diagnosis was ascites. Only 56% of confirmed cases had an accompanying diagnosis code for cirrhosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our ICD\u201010\u2010based coding algorithm identified hepatic decompensation with high PPV in Veterans Health Administration data.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pds.70024","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T02:40:02Z","timestamp":1730342402000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Validated Algorithm to Identify Hepatic Decompensation in the Veterans Health Administration Electronic Health Record System"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6650-0978","authenticated-orcid":false,"given":"Lamia Y.","family":"Haque","sequence":"first","affiliation":[{"name":"Section of Digestive Diseases, Department of Internal Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"Veterans Affairs Connecticut Healthcare System  West Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet P.","family":"Tate","sequence":"additional","affiliation":[{"name":"Veterans Affairs Connecticut Healthcare System  West Haven Connecticut USA"},{"name":"Department of Internal Medicine\u2014Section of General Internal Medicine Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chew","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases, Department of Internal Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"Veterans Affairs Connecticut Healthcare System  West Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen C.","family":"Caniglia","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, and Informatics Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar H.","family":"Taddei","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases, Department of Internal Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"Veterans Affairs Connecticut Healthcare System  West Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7955-0600","authenticated-orcid":false,"suffix":"III","given":"Vincent Lo","family":"Re","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, and Informatics Perelman School of Medicine  Philadelphia Pennsylvania USA"},{"name":"Division of Infectious Diseases, Department of Medicine; Center for Clinical Epidemiology and Biostatistics Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k2817"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.10.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650\u2010200411000\u201000005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.2148"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.01.042"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.12.017"},{"key":"e_1_2_10_8_1","unstructured":"U. 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