{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T01:15:51Z","timestamp":1787102151342,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Key changes in the pharmacoepidemiological research environment had a significant influence on the activities of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP) over the last decade. These changes included the SARS\u2010CoV\u20102 pandemic, the increased access to anonymized real\u2010world data (RWD) sources, the integration of real\u2010world evidence (RWE) into regulatory and public health decision\u2010making, and the emergence of new technologies and methods. This paper describes how ENCePP has evolved in this changing environment to strengthen pharmacoepidemiological methods and practice in Europe and globally. It also provides future perspectives for the network. Through a collaborative approach in non\u2010interventional research, ENCePP will collectively continue to promote excellence for RWE generation, supporting the safe and effective use of medicines.<\/jats:p>","DOI":"10.1002\/pds.70263","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T01:04:44Z","timestamp":1762995884000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Strengthening Pharmacoepidemiology in a Changing Research Environment: The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (\n                    <scp>ENCePP<\/scp>\n                    )"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8839-4549","authenticated-orcid":false,"given":"Xavier","family":"Kurz","sequence":"first","affiliation":[{"name":"European Specialised Expert Community European Medicines Agency  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cohet","sequence":"additional","affiliation":[{"name":"Real\u2010World Evidence Workstream, Data Analytics and Methods Task Force European Medicines Agency  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5798-3691","authenticated-orcid":false,"given":"Susana","family":"Perez\u2010Gutthann","sequence":"additional","affiliation":[{"name":"Regulatory Grade RWE &amp; 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