{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:48:07Z","timestamp":1789289287196,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Ascertaining migraine in electronic healthcare data is challenging because of likely diagnosis underrecording and treatment with over\u2010the\u2010counter analgesics, which cannot be used as disease proxies. Algorithm\u2010identified migraine prevalence may depend on algorithm characteristics and target population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>To describe migraine\u2010identifying algorithms implemented in electronic healthcare data sources and summarize validation results and observed migraine prevalence, we searched PubMed for peer\u2010reviewed, English\u2010language, original research articles that identified migraine in adults using electronic algorithms in electronic healthcare data. We summarized algorithms, validation results, and migraine prevalence (PROSPERO: CRD42023491279).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 360 unique titles and abstracts, 50 articles (14%) were selected for full\u2010text review; of them, 41 articles (82%) were finally included: 16 were studies conducted in Europe, 13 in North America, and 12 in Asia. Sixteen studies (39%) identified migraine only using diagnosis codes, 5 (12%) only treatments, 9 (22%) diagnosis and\/or treatment codes, and 11 (27%) diagnosis codes, treatments, and setting (e.g., primary care, specialist consultation). Reported migraine prevalence in the general population ranged between 4% and 17%. Only two studies reported validation results: one identified prevention\u2010eligible patients with migraine (positive predictive value [PPV]\u2009=\u200997%), and one identified migraine on the basis of calculated probabilities with PPVs between 74% and 92%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Finding patients with migraine is feasible in various types of data sources; preferred algorithms vary; algorithm performance is mostly unknown. Identifying chronic migraine or other complex types of migraine requires combining diagnosis codes, treatments, and care settings, which is possible in only some data sources.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pds.70278","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T04:30:32Z","timestamp":1764736232000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Challenges for Pharmacoepidemiologists Identifying Migraine in Electronic Healthcare Data Sources: A Systematic Literature Review"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1066-0358","authenticated-orcid":false,"given":"Joan","family":"Forns","sequence":"first","affiliation":[{"name":"Pharmacoepidemiology and Risk Management, RTI Health Solutions  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6552-6060","authenticated-orcid":false,"given":"Alicia","family":"Abellan","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology and Risk Management, RTI Health Solutions  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9482-7524","authenticated-orcid":false,"given":"Nuria","family":"Riera\u2010Gu\u00e0rdia","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology and Risk Management, RTI Health Solutions  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7388-6082","authenticated-orcid":false,"given":"Andrea V.","family":"Margulis","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology and Risk Management, RTI Health Solutions  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5093-2445","authenticated-orcid":false,"given":"Elena","family":"Rivero\u2010Ferrer","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology and Risk Management, RTI Health Solutions  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474\u20104422(18)30322\u20103"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468\u20102982.2009.01941.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2021.03.001"},{"key":"e_1_2_10_6_1","volume-title":"Checklist for Prevalence Studies","author":"The Joanna Briggs Institute","year":"2020"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.30385"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1004238"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010023\u201001558\u20105"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010022\u201001513\u2010w"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2023.2207413"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933\u2010022\u201001705\u20103"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2022.28.11.1272"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010022\u201001476\u2010y"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010022\u201008191\u2010z"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120\u2010021\u201000304\u2010w"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2021.68"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940\u2010021\u201000727\u2010w"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/s2045796021000421"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102020\u2010038972"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2020.1814790"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010020\u201001166\u20107"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010020\u201001154\u2010x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419889351"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2019.1657716"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2018.18058"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419856630"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419851855"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102019\u2010029147"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010027251"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.4723"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010019\u20100964\u20105"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.0939"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010018\u20100889\u20104"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13275"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k96"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13157"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.12.019"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102416678382"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.08.055"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000003670"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415590242"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000003065"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000002646"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2015.10.005"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcu215"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194\u2010015\u20100547\u2010z"}],"container-title":["Pharmacoepidemiology and Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pds.70278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T07:27:50Z","timestamp":1767079670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pds.70278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":46,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/pds.70278"],"URL":"https:\/\/doi.org\/10.1002\/pds.70278","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.22541\/au.173781278.87655336\/v1","asserted-by":"object"}]},"ISSN":["1053-8569","1099-1557"],"issn-type":[{"value":"1053-8569","type":"print"},{"value":"1099-1557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70278"}}