{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:03:32Z","timestamp":1789657412309,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>A pharmacotherapeutic follow\u2010up service is attended by pharmacists who systematically identify drug\u2010related problems and work to resolve their associated negative outcomes. The aim was to describe the characteristics of a pharmacotherapeutic follow\u2010up service and the factors associated with the presentation of drug\u2010related problems in a group of patients affiliated to the Colombian Health System.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a cross\u2010sectional study of patients who attended a DADER method\u2010based pharmacotherapeutic follow\u2010up service. The drug\u2010related problems and their associated negative outcomes as well as the interventions performed on the patients were identified. Descriptive analysis and binary logistic regression were performed considering the presence of drug\u2010related problems as a dependent variable (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 18\u2009563 patients were identified, with an average age of 64.8\u2009\u00b1\u200914.9\u2009years, and 66.3% were women. The most common chronic diseases were hypertension (54.3%), diabetes mellitus (29.2%), and rheumatoid arthritis (25.9%). The average number of medications\/patient was 5.0\u2009\u00b1\u20094.1. Drug\u2010related problems were documented for 60.8% of the patients (1.6 drug\u2010related problems\/patient), mainly due to drug\u2013drug interactions (25.4%). Negative outcomes associated with medication use were observed for 60.0% of the patients (42.0% predominantly related to safety). The most common intervention was patient education (50.9%), and the negative outcomes associated with Medication use were resolved for 31.1% of patients who had two or more consultations. Patients over 65\u2009years of age (OR:1.20; 95% CI:1.06\u20131.36), those from Bogot\u00e1\u2013Cundinamarca (OR:1.62; 95% CI:1.52\u20131.73), those treated with \u2265\u200910 drugs (OR:1.21; 95% CI:1.07\u20131.36) and those treated with anticoagulants (OR:1.91; 95% CI:1.70\u20132.14) were more likely to experience drug\u2010related problems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Drug\u2010related problems were frequently identified, with drug\u2013drug interactions being the most prevalent problem. Drug\u2010related problems were associated with increased age, an increased number of prescribed medications and the use of anticoagulants. Safety\u2010related negative outcomes associated with medication use were common, education was the predominant intervention, and one\u2010third of the negative outcomes associated with medication use were resolved.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pds.70366","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:35:26Z","timestamp":1775561726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacotherapeutic Monitoring and Drug\u2010Related Problems in a Group of Patients From Colombia: Cross\u2010Sectional Study, 2023\u20132024"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4245-0101","authenticated-orcid":false,"given":"Luis Fernando","family":"Valladales\u2010Restrepo","sequence":"first","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Farmacoepidemiolog\u00eda y Farmacovigilancia Universidad 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