{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T02:02:38Z","timestamp":1784512958323,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2024\/07284\u20109"],"award-info":[{"award-number":["2024\/07284\u20109"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacoepidemiology and Drug"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Venous thromboembolism (VTE) is a preventable condition associated with an increased risk of morbidity and mortality in hospitalized patients. Pharmacological and\/or mechanical prophylaxis can prevent thromboembolism events. Guidelines recommend the use of scores for risk assessment in hospitalized patients. These scores are based on a variety of risk factors, including age, reduced mobility, and type of surgery. They help determine the most appropriate prophylaxis method for each patient. However, VTE prophylaxis is still a challenge, and there are limitations associated with it. In this scenario, clinical pharmacists may play a key role in improving VTE prophylaxis. The main aim of this real\u2010life study was to evaluate the contribution of the clinical pharmacist to thromboembolism prophylaxis in a large sample of clinical and surgical patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is an observational and retrospective study using hospital\u2010based data. The study included 4031 patients, and we evaluated how pharmacist interventions contributed to the appropriate indication and correct use of VTE prophylaxis in clinical and surgical patients. We included 1093 clinical patients and 2938 surgical patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Following clinical pharmacist involvement (262 pharmacist interventions), there were improvements in the adequacy rate: 62.0% for clinical patients and 55.0% for surgical patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The intervention of the clinical pharmacist can contribute to improved rates of adherence to VTE protocols.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pds.70418","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T11:56:45Z","timestamp":1781697405000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Pharmacist Intervention Improves Adherence to Venous Thromboembolism Protocols"],"prefix":"10.1002","volume":"35","author":[{"given":"Anne Karollyne Soares Silva","family":"Leite","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Escola Paulista de Medicina Universidade Federal de S\u00e3o Paulo, EPM\u2010Unifesp  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leiliane Rodrigues","family":"Marcatto","sequence":"additional","affiliation":[{"name":"Laboratory of Genetics and Molecular Cardiology, Instituto Do Cora\u00e7\u00e3o, Hospital das Cl\u00ednicas, HCFMUSP, Faculdade de Medicina Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Eduardo Nascimento Silva","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Escola Paulista de Medicina Universidade Federal de S\u00e3o Paulo, EPM\u2010Unifesp  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Hospital Santa Paula  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael Bruno Rocha","family":"Tolentino","sequence":"additional","affiliation":[{"name":"Hospital Santa Paula  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8297-0793","authenticated-orcid":false,"given":"Paulo Caleb Junior Lima","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Escola Paulista de Medicina Universidade Federal de S\u00e3o Paulo, EPM\u2010Unifesp  S\u00e3o Paulo Brazil"},{"name":"Department of Clinical and Toxicology Analysis, Faculty of Pharmacy Universidade Federal de Alfenas  Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/jrpp.JRPP_16_160"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-022-00787-6"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-13-203"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3_suppl.338S"},{"key":"e_1_2_10_6_1","unstructured":"Brazilian Medical Association; Federal Council of Medicine Venous Thromboembolism: Prophylaxis in Clinical Patients 2005."},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2296"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043169"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60202-0"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1679-45082014AO2526"},{"key":"e_1_2_10_11_1","first-page":"92","volume-title":"Preventing Hospital\u2010Associated Venous Thromboembolism: A Guide for Effective Quality Improvement","author":"Maynard G.","year":"2015"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tru.2023.100132"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-014-9988-8"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.03.002"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcae045"},{"issue":"3","key":"e_1_2_10_16_1","first-page":"463","article-title":"Anticoagulation Stewardship: Improving Adherence to Clinical Guidelines and Reducing Overuse of Venous Thromboembolism Prophylaxis in Hospitalized Medical Patients","volume":"21","author":"Gillespie B.","year":"2024","journal-title":"Research in Social & Administrative Pharmacy"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2005.11.9.755"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-018-3557-0"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp070595"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2289"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp110187"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.01461"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.18549\/PharmPract.2019.4.1541"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/2042098619863985"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-011-0614-5"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2011.11.2499"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S171745"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1244"}],"container-title":["Pharmacoepidemiology and Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pds.70418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pds.70418","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pds.70418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T01:41:50Z","timestamp":1784511710000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pds.70418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,17]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/pds.70418"],"URL":"https:\/\/doi.org\/10.1002\/pds.70418","archive":["Portico"],"relation":{},"ISSN":["1053-8569","1099-1557"],"issn-type":[{"value":"1053-8569","type":"print"},{"value":"1099-1557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,17]]},"assertion":[{"value":"2025-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70418"}}