{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T19:57:26Z","timestamp":1784404646166,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T00:00:00Z","timestamp":1561420800000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Investigation"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Importance<\/jats:title><jats:p>Pectus excavatum (<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>) is the most common thoracic wall deformity in children, we need a method which could be used to evaluate pulmonary functions and effects on development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the use of 3D T1\u2010weighted (3<jats:styled-content style=\"fixed-case\">DT<\/jats:styled-content>1) and <jats:styled-content style=\"fixed-case\">mDIXON<\/jats:styled-content> magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) sequences for measuring the thoracic parameters and morphology of children with <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>, comparing the measurements with those made on computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study of children with thoracic deformities who were hospitalized at the Department of Thoracic Surgery of the Heart Center, Beijing Children's Hospital, between June 2014 and June 2015. Chest <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> was performed first, with the <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scanning then being performed 0\u20133 days later. The <jats:styled-content style=\"fixed-case\">mDIXON<\/jats:styled-content> sequences were obtained in inspiratory and expiratory phases and the 3<jats:styled-content style=\"fixed-case\">DT<\/jats:styled-content>1 sequences were obtained during free breathing. Thoracic volume was measured using the acquired images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The lung volumes measured on <jats:styled-content style=\"fixed-case\">mDIXON MRI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> were highly correlated, with the Haller index not being significantly different between the two methods. Bland\u2010Altman analyses showed that lung, cardiac, and retrosternal parameters were similar between the two methods. Pulmonary parameters were higher with the end\u2010inspiratory phase <jats:styled-content style=\"fixed-case\">mDIXON<\/jats:styled-content> images than with the end\u2010expiratory phase images, as expected, while cardiac parameters were unaffected by the respiratory phase.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Thoracic volumes measured on <jats:styled-content style=\"fixed-case\">mDIXON MRI<\/jats:styled-content> in combination with held respiration could reflect lung volume functions and help in observing the movement functions of the lungs and heart. The method could be used instead of <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>, avoiding subjecting the patient to potentially harmful radiation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ped4.12132","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T21:28:49Z","timestamp":1561498129000},"page":"102-109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of magnetic resonance imaging and computed tomography to measure preoperative parameters of children with pectus excavatum"],"prefix":"10.1002","volume":"3","author":[{"given":"Jihang","family":"Sun","sequence":"first","affiliation":[{"name":"Imaging Center Beijing Children's Hospital Capital Medical University National Center for Children's Health Beijing 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