{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T04:40:08Z","timestamp":1750308008048,"version":"3.41.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Investigation"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Horner syndrome (HS) is a rare neurological disorder arising from disruption of the oculosympathetic pathway. Pediatric HS is uncommon and may be congenital, but underlying sinister causes need to be excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>An 18\u2010week\u2010old boy presented with right peri\u2010orbital swelling, initially thought to be pre\u2010septal cellulitis. Further ophthalmic review revealed a right\u2010sided HS. Imaging identified a probable cervical neuroblastoma, leading to an urgent referral to oncology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early recognition of pediatric HS is crucial as it may signal underlying malignancies like neuroblastoma. Atypical presentations with sequential or intermittent symptoms make diagnosis challenging. Comprehensive imaging and multidisciplinary care ensure timely diagnosis and management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ped4.12470","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T14:46:48Z","timestamp":1739544408000},"page":"167-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Horner syndrome in a pediatric patient"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8737-1511","authenticated-orcid":false,"given":"Devansh","family":"Tandon","sequence":"first","affiliation":[{"name":"University College London Medical School  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Azzopardi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Royal Free NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic","family":"Fenn","sequence":"additional","affiliation":[{"name":"Paediatrics Whittington Health NHS Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mira","family":"Parmar","sequence":"additional","affiliation":[{"name":"Paediatrics West Hertfordshire Teaching Hospitals NHS Trust  Watford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurabh","family":"Jain","sequence":"additional","affiliation":[{"name":"University College London Medical School  London UK"},{"name":"Department of Ophthalmology Royal Free NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_1","DOI":"10.1002\/cphy.c140014"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.3390\/vision6010006"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.1001\/archophthalmol.2010.6"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_1","DOI":"10.1007\/s00415\u2010020\u201010270\u20102"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1038\/s41433\u2010020\u20100967\u20100"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_1","DOI":"10.1016\/B978\u20100\u201012\u2010380916\u20102.00004\u20108"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_1","DOI":"10.1056\/NEJMra0804577"},{"doi-asserted-by":"publisher","key":"e_1_2_6_9_1","DOI":"10.1200\/JCO.1988.6.8.1271"},{"doi-asserted-by":"publisher","key":"e_1_2_6_10_1","DOI":"10.1001\/archophthalmol.2010.119"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_1","DOI":"10.1001\/archopht.1969.00990010707018"},{"doi-asserted-by":"publisher","key":"e_1_2_6_12_1","DOI":"10.1200\/JCO.2007.12.3349"},{"doi-asserted-by":"publisher","key":"e_1_2_6_13_1","DOI":"10.1097\/SLA.0b013e31826cbbbd"},{"doi-asserted-by":"publisher","key":"e_1_2_6_14_1","DOI":"10.1200\/JCO.1998.16.6.2003"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_1","DOI":"10.1038\/nrdp.2016.78"},{"doi-asserted-by":"publisher","key":"e_1_2_6_16_1","DOI":"10.1056\/NEJMoa1001527"},{"doi-asserted-by":"publisher","key":"e_1_2_6_17_1","DOI":"10.3389\/fneur.2019.00055"},{"doi-asserted-by":"publisher","key":"e_1_2_6_18_1","DOI":"10.1016\/j.jaapos.2007.02.015"},{"doi-asserted-by":"publisher","key":"e_1_2_6_19_1","DOI":"10.1542\/peds.62.1.77"},{"key":"e_1_2_6_20_1","first-page":"1995","article-title":"Urinary excretion of 3\u2010methoxy\u20104\u2010hydroxymandelic acid and 3\u2010methoxy\u20104\u2010hydroxyphenylacetic acid by 288 patients with neuroblastoma and related neural crest tumors","volume":"40","author":"LaBrosse EH","year":"1980","journal-title":"Cancer Res."},{"doi-asserted-by":"publisher","key":"e_1_2_6_21_1","DOI":"10.1016\/j.ejca.2016.12.002"}],"container-title":["Pediatric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ped4.12470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T15:06:32Z","timestamp":1750259192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ped4.12470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,14]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/ped4.12470"],"URL":"https:\/\/doi.org\/10.1002\/ped4.12470","archive":["Portico"],"relation":{},"ISSN":["2096-3726","2574-2272"],"issn-type":[{"type":"print","value":"2096-3726"},{"type":"electronic","value":"2574-2272"}],"subject":[],"published":{"date-parts":[[2025,2,14]]},"assertion":[{"value":"2024-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}