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The preferred strategy for preventing <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content> is optimal medical management; however, for patients who develop <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content>, delaying disease progression through effective medication management is equally important. A review of the literature regarding medication management of <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content> was conducted via a search of the <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content> database. Studies were included if they were published in English, conducted in humans \u2265\u00a018\u00a0years of age or older, and used noninvestigational medications. Immunosuppressive medications such as the antiproliferative mycophenolate, the calcineurin inhibitor tacrolimus, and the proliferation signal inhibitors sirolimus and everolimus have been shown to prevent the development of <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content>. Certain cardiovascular medications, such as <jats:styled-content style=\"fixed-case\">HMG<\/jats:styled-content>\u2010CoA reductase inhibitors (statins), gemfibrozil, calcium channel blockers, and angiotensin\u2010converting enzyme inhibitors, have also demonstrated efficacy in preventing this disease process. Prevention of <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content> has also been observed with prophylaxis against cytomegalovirus infection and antioxidant medications. Despite being commonly used in <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content> patients, neither antiplatelet agents nor glycemic control have proved effective at preventing <jats:styled-content style=\"fixed-case\">CAV<\/jats:styled-content>. 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