{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:17:53Z","timestamp":1790637473375,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T00:00:00Z","timestamp":1483660800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Because estrogens and the trigeminal system are inherently linked, prescribers who are treating a woman with a hormonally related mood disorder and migraine headaches should consider hormonal options to optimize the patient's treatment. This article discusses the interrelationships of estrogen, serotonin, and the trigeminal system as they relate to menstrual migraine occurrence and hormone\u2010related mood symptoms. In addition, clinical examples are provided to facilitate the prescribers treating women during reproductive transitions in which declining estrogens are related to their suffering.<\/jats:p>","DOI":"10.1002\/phar.1876","type":"journal-article","created":{"date-parts":[[2016,11,26]],"date-time":"2016-11-26T03:56:40Z","timestamp":1480132600000},"page":"120-128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Hormone\u2010Related Migraine Headaches and Mood Disorders: Treatment with Estrogen Stabilization"],"prefix":"10.1002","volume":"37","author":[{"given":"Julia K.","family":"Warnock","sequence":"first","affiliation":[{"name":"Department of Psychiatry School of Community Medicine University of Oklahoma Tulsa OK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Pharmacotherapy, UNT System College of Pharmacy University of North Texas Health Sciences Center Fort Worth Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey","family":"Blumenthal","sequence":"additional","affiliation":[{"name":"Department of Psychiatry School of Community Medicine University of Oklahoma Tulsa OK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan E.","family":"Hammond","sequence":"additional","affiliation":[{"name":"College of Medicine University of Oklahoma Tulsa OK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.1.199"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0511-10.2010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1985.hed2507376.x"},{"key":"e_1_2_6_5_1","first-page":"1017","article-title":"Hormone\u2010related headache","volume":"85","author":"Silberstein S","year":"2001","journal-title":"Headache"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12640"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00370.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Premenstrual dysphoric disorder. In: Diagnostic and statistical manual of mental disorders: DSM\u20105","author":"American Psychiatric Association","year":"2013"},{"key":"e_1_2_6_9_1","first-page":"50","article-title":"A new horizon into the pathobiology, etiology, and treatment of migraine","volume":"3","author":"Dhillon K","year":"2011","journal-title":"Med Hypotheses"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2001.00244.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.22.4.355"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-008-0077-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(95)00052-T"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000249114.52802.55"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0885-3924(93)90107-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-011-0200-8"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5122(93)90121-W"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000058907.41080.54"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01309.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182535d20"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182535d0c"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200822100-00007"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.00819.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02140.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.01.013"},{"key":"e_1_2_6_26_1","volume-title":"Drugs in pregnancy and lactation: a reference guide to fetal and neonatal risk","author":"Briggs GB","year":"2015"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-010-0174-7"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00554.x"},{"key":"e_1_2_6_29_1","unstructured":"Centers for Disease Control and Prevention. Reproductive Health. United States Medical Eligibility Criteria (US MEC) for Contraceptive Use; 2016. Available fromhttp:\/\/www.cdc.gov\/reproductivehealth\/contraception\/usmec.htm. Accessed September 14 2016."},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0193-953X(03)00042-X"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12763"}],"container-title":["Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fphar.1876","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/phar.1876","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T09:59:31Z","timestamp":1761040771000},"score":1,"resource":{"primary":{"URL":"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/10.1002\/phar.1876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1002\/phar.1876"],"URL":"https:\/\/doi.org\/10.1002\/phar.1876","archive":["Portico"],"relation":{},"ISSN":["0277-0008","1875-9114"],"issn-type":[{"value":"0277-0008","type":"print"},{"value":"1875-9114","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}