{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:40:51Z","timestamp":1761093651375,"version":"build-2065373602"},"reference-count":59,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>Recent hypertension clinical trials and national guideline updates have created a debate on the most appropriate treatment goals in elderly patients with hypertension. In 2014, recommendations by the Eighth Joint National Committee allowed a more lenient goal for patients 60\u00a0years and older compared with previous guidelines. Since then, several large clinical trials and meta\u2010analyses have added more information regarding strict versus lenient treatment goals. Most recently, the American College of Cardiology and American Heart Association Task Force published their highly anticipated hypertension guideline developed in conjunction with nine additional interdisciplinary organizations. This review discusses the culmination of emerging data to provide more insight into the treatment of hypertension in the elderly. A literature search was conducted using PubMed, the Cumulative Index of Nursing and Allied Health, the Cochrane database, and by hand\u2010searching references from relevant articles. The following key terms were used: <jats:italic>hypertension, blood pressure, systolic,<\/jats:italic> and <jats:italic>elderly<\/jats:italic>. Available literature suggests that it is reasonable to target an office systolic blood pressure of less than 130\u00a0mm\u00a0Hg in elderly patients with hypertension. An individualized approach is reasonable for those who are institutionalized, with high comorbidity burden, or have a short life expectancy. A diastolic blood pressure of less than 60\u00a0mm\u00a0Hg should be avoided due to the potential for an increase in cardiovascular risk. The method of blood pressure measurement is extremely important to consider when determining the blood pressure goal, and proper procedures for accurate blood pressure measurement must be followed. Other factors important to consider may include the patient's comorbidities, frailty, as well as the patient's potential for adverse drug reactions.<\/jats:p>","DOI":"10.1002\/phar.2081","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T00:49:30Z","timestamp":1515545370000},"page":"370-381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Considerations for Optimal Blood Pressure Goals in the Elderly Population: A Review of Emergent Evidence"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6083-837X","authenticated-orcid":false,"given":"Diana X.","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Clinical and Administrative Sciences College of Pharmacy California Northstate University Elk Grove California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca J. 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