{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:34:18Z","timestamp":1790685258248,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacotherapy"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Monoclonal antibodies acting on the calcitonin gene\u2010related peptide or its receptor (CGRP\u2010mabs) are novel drugs for resistant migraine prophylaxis. As CGRP\u2010mabs cause inhibition of vasodilatation, their use is reserved to patients with no recent history of cardiovascular diseases. We report a case of myocardial infarction associated with erenumab.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case<\/jats:title><jats:p>A 57\u2010year\u2010old woman with a familial history of coronaropathy was first treated with erenumab 70\u2009mg for 6\u2009months and then increased to 140\u2009mg. Almost 5\u2009months after, the patient presented chest pain, increased troponin, and abnormal electrocardiogram. A myocardial infarction without coronarography abnormality was diagnosed through MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Further evidence is needed to assess the risk of myocardial infarction in patients treated with a CGRP\u2010mab. In patients over 40\u2009years of age, the risk of coronary or cardiovascular events should be assessed using risk tables or algorithms to take into account cardiovascular risk factors. This may be complemented by appropriate examinations to measure the burden of coronary atherosclerosis, if necessary.<\/jats:p><\/jats:sec>","DOI":"10.1002\/phar.2706","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T04:29:08Z","timestamp":1653625748000},"page":"585-589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Myocardial infarction associated with erenumab: A case report"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0039-0734","authenticated-orcid":false,"given":"Justine","family":"Perino","sequence":"first","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"},{"name":"Univ. Bordeaux, INSERM, BPH, U1219  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Corand","sequence":"additional","affiliation":[{"name":"Pain Center of Bordeaux, Department of Clinical Neurosciences University Hospital of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Laurent","sequence":"additional","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Th\u00e9ophile","sequence":"additional","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghada","family":"Miremont\u2010Salam\u00e9","sequence":"additional","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Pariente","sequence":"additional","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"},{"name":"Univ. Bordeaux, INSERM, BPH, U1219  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Laurent","family":"Colas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Polyclinique Bordeaux Nord Aquitaine  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Couffinhal","sequence":"additional","affiliation":[{"name":"Univ. Bordeaux, INSERM, Biology of Cardiovascular Diseases, U1034, CHU de Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3210-7171","authenticated-orcid":false,"given":"Francesco","family":"Salvo","sequence":"additional","affiliation":[{"name":"Pharmacovigilance Center of Bordeaux, Department of Medical Pharmacology University Hospital of Bordeaux  Bordeaux France"},{"name":"Univ. 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