{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T12:46:31Z","timestamp":1765111591212,"version":"3.46.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pregnancy"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Current recommendations for intrapartum glycemic control in those with diabetes mellitus are based upon expert opinion. Our objective was to characterize intrapartum interstitial glucose values using continuous glucose monitors (CGMs) in term gravidas without diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective observational cohort of 72 parturients without pre\u2010gestational or gestational diabetes. CGMs were placed in early labor and the following were obtained: glucose at delivery, mean glucose in active and second stage of labor, time in range defined as 70\u2013120\u00a0mg\/dL, time above range, and time below range. Glucose parameters were compared by body mass index (BMI) and by adequacy of gestational weight gain. Neonatal outcomes were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean glucose value at delivery was 109\u00a0\u00b1\u00a027\u00a0mg\/dL and over the 2\u00a0h prior to delivery was 99\u00a0\u00b1\u00a023\u00a0mg\/dL. A total of 26% of parturients had a glucose\u00a0value &gt;\u00a0120\u00a0mg\/dL at the time of delivery. Mean glucose in active labor was 101\u00a0\u00b1\u00a025\u00a0mg\/dL and in the second stage was 99.5\u00a0\u00b1\u00a023\u00a0mg\/dL. In labor, average time\u2010in\u2010range was 69.8% (10th\u201390th percentile 33.8%\u201395.8%), time\u2010above\u2010range was 19.9% (10th\u201390th percentile 0%\u201366.2%), and time\u2010below\u2010range was 10.3% (10th\u201390th percentile 0%\u201366%). Neither BMI nor gestational weight gain had a significant clinical impact on these parameters. A total of 28 infants had glucose checked for clinical indications and 5 required treatment for neonatal hypoglycemia; this was unrelated to mean glucose during labor or at delivery, time\u2010above\u2010range in labor and second stage, and time\u2010above\u2010range in the 4\u00a0h prior to delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Interstitial glucose greater than 120\u00a0mg\/dL was common, and neither BMI nor gestational weight gain appears to have a significant clinical impact on glucose in labor. These data challenge contemporary definitions of glucose goals in labor, and further study is needed to better define glucose in labor and identify risk factors for adverse outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmf2.70108","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:20:16Z","timestamp":1758932416000},"source":"Crossref","is-referenced-by-count":0,"title":["Characterizing glucose in labor: Continuous glucose monitoring in parturients without diabetes"],"prefix":"10.1002","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5352-7787","authenticated-orcid":false,"given":"Kelsey","family":"Pinson","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics Gynecology, and Reproductive Sciences University of California, San Diego  La Jolla California USA"},{"name":"Legacy Emanuel Medical Center Legacy Medical Group\u2014Maternal Fetal Medicine  Portland Oregon USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane J.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology Department of Pediatrics University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navyaa","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Medicine University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9041-5167","authenticated-orcid":false,"given":"Emily","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Medicine University of California, San Diego  La Jolla California USA"},{"name":"Bioinformatics and Systems Biology Graduate Program University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit R.","family":"Majithia","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Medicine University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Stanley","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics Gynecology, and Reproductive Sciences University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gladys A.","family":"Ramos","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics Gynecology, and Reproductive Sciences University of California, San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.1579"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892\u2010013\u20100450\u20104"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0029\u20107844(01)01790\u20102"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002960"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2024.05.053"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968221126995"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968221113865"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-S007"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2018.0364"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296817704443"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296815590154"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/193229681000400325"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.51.2007.S271"},{"volume-title":"Dexcom G6 Continuous Glucose Monitoring System User Guide","key":"e_1_2_11_15_1","first-page":"92121"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6659.1304"},{"volume-title":"Weight Gain during Pregnancy: Reexamining the Guidelines","year":"2009","author":"Institute of Medicine","key":"e_1_2_11_17_1"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aog.0000425668.87506.4c"},{"key":"e_1_2_11_19_1","unstructured":"Python 3.10.4 Documentation Released on March 24 2022. 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