{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T12:45:39Z","timestamp":1765111539242,"version":"3.46.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004888","name":"Illinois Department of Public Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004888","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pregnancy"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess effective implementation strategies to reduce time to treatment for severe maternal hypertension and drivers of culture change among high\u2010performing sites in a statewide quality improvement (QI) initiative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using a mixed\u2010methods sequential explanatory design, mixed effect linear regression models with a logit link were used to assess the association between achievement of system changes at each hospital and the proportion of cases in which time to treatment was achieved, including fixed effects for system changes and time (quarter of implementation year) and random effects for hospital and quarter within hospital (random slope). All models were adjusted for birth volume, location (urban\/rural), and patient population demographics, and a sensitivity analysis was performed for multiple comparisons. Then, key informant interviews of 11 high\u2010performing hospital teams explored implementation strategies driving system and clinical culture change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 108 participating hospitals, 79 submitted quarterly survey data on progress toward implementing system changes. Our quantitative analysis demonstrated that several individual system changes were initially associated with a reduction in time to treatment for maternal hypertension, but these associations were not significant after adjusting for multiple comparisons. Through qualitative interviews, we learned that high\u2010performing sites enacted the system changes which showed initial promise in our quantitative analysis by reducing burden for their QI teams by utilizing existing QI support, educating clinical teams and patients to empower them as agents of behavior change, promoting clinician engagement using multi\u2010level strategies, optimizing workflow and infrastructure, and fostering innovation based on other teams\u2019 experiences. Key drivers of clinical culture change included hospital environments that emphasized communication at the patients\u2019 bedside around QI priorities, valued interprofessional relationships and communication, promoted shared values around providing high\u2010quality maternal care and protecting maternal safety, and harnessed external support from professional societies and leadership.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This mixed\u2010methods analysis identifies key implementation strategies that perinatal quality collaboratives and individual hospitals can utilize to sustain behavior change to reduce time to treatment for severe maternal hypertension. While we were unable to definitively identify singular system changes that reduced time to treatment, our qualitative data suggest that a combination of these changes may change clinical culture and lead to improved outcomes. Future work to assess the impact of selected system changes as well as clinical culture change on obstetric QI efforts is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmf2.70116","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T08:40:16Z","timestamp":1758876016000},"source":"Crossref","is-referenced-by-count":0,"title":["Effective implementation strategies and drivers of culture change for improving time to treatment for severe maternal hypertension"],"prefix":"10.1002","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0687-3668","authenticated-orcid":false,"given":"Natasha R.","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4837-4138","authenticated-orcid":false,"given":"Patricia Ann Lee","family":"King","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences and Center for Healthcare Studies, Feinberg School of Medicine Northwestern University  Chicago Illinois USA"},{"name":"Department of Obstetrics and Gynecology The University of Chicago Pritzker School of Medicine  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Welty","sequence":"additional","affiliation":[{"name":"Biostatistics Collaboration Center, Department of Preventive Medicine Northwestern University Feinberg School of Medicine  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Borders","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences and Center for Healthcare Studies, Feinberg School of Medicine Northwestern University  Chicago Illinois USA"},{"name":"Department of Obstetrics and Gynecology The University of Chicago Pritzker School of Medicine  Chicago Illinois USA"},{"name":"Department of Obstetrics and Gynecology Endeavor Health (formally NorthShore University HealthSystem), Evanston Hospital  Evanston Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.07.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.01.176"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003290"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000151116.84113.56"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.07.010"},{"key":"e_1_2_9_7_1","first-page":"67","article-title":"ACOG Practice Bulletin. 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