{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:54:13Z","timestamp":1791986053919,"version":"4.4.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Hemoglobin levels are typically checked 4\u00a0h after transfusion to assess response, but this delay is unnecessary in nonpregnant adult patients. It remains unclear if postpartum patients need time for hemoglobin levels to stabilize due to post\u2010delivery pregnancy physiology. This study aims to determine if immediate reassessment of hemoglobin following transfusion is sufficient for postpartum patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This is a single\u2010center, prospective study from February to July 2025 in which serial hemoglobin assessments (immediate, 4\u00a0h, 12\u00a0h after transfusion) were completed following the transfusion of packed red blood cells (PRBCs). Exclusion criteria were the following: hemodynamic instability,\u00a0&gt;72\u00a0h from delivery, massive transfusion protocol activation,\u00a0more than four units PRBC transfused, or missed lab draw timing\u00a0&gt;15 min. Power analysis determined that 23 patients would be needed for 80% power to detect a difference of 0.6\u00a0g\/dL using paired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests with a two\u2010sided\n                      <jats:italic>p<\/jats:italic>\n                      value of\u00a0&lt;0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010four participants met the criteria and were enrolled. When compared to 12\u2010h posttransfusion hemoglobin, there was no difference between hemoglobin concentration in g\/dL between the immediate (0.08\u00a0g\/dL; 95% confidence interval [CI], \u22120.44 to 0.26) and 4\u2010h posttransfusion (0.10\u00a0g\/dL; 95% CI, \u22120.41 to 0.21) values. The mean immediate rise in hemoglobin for those with one unit transfused was 0.97\u00a0g\/dL (95% CI, 0.48\u20131.45) and for those with two units transfused was 1.99\u00a0g\/dL (95% CI, 1.26\u20132.71).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings indicate that hemoglobin equilibration occurs rapidly following PRBC transfusion in stable postpartum patients, and that an arbitrary 4\u2010h delay after the completion of transfusion before laboratory reassessment is not necessary. Earlier evaluation of response to transfusion could prevent delays in anemia management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmf2.70248","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T08:02:25Z","timestamp":1770796945000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hemoglobin equilibration after transfusion in stable postpartum patients"],"prefix":"10.1002","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6239-8427","authenticated-orcid":false,"given":"Aaron W.","family":"Roberts","sequence":"first","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Crowe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Zaki","family":"Moustafa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan C.","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baha","family":"Sibai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean C.","family":"Blackwell","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology and Reproductive Sciences McGovern Medical School at UTHealth Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.07.007"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002351"},{"key":"e_1_2_10_4_1","volume-title":"Pregnancy Mortality Surveillance System","author":"Centers for Disease Control and Prevention, U.S. Department of Health and Human 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