{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:49:41Z","timestamp":1791532181356,"version":"4.3.4"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006928","name":"Ohio State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006928","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      Pregnant women with type 1 diabetes (T1D) increasingly utilize hybrid closed\u2010loop (HCL) pumps, but\n                      <jats:italic>pregnancy\u2010specific<\/jats:italic>\n                      algorithms in many countries including the United States are not available. We compared pregnancy and glycemic outcomes between those intending to use off\u2010label automated HCL versus manual sensor\u2010augmented pump therapy (SAPT).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single\u2010center retrospective study from 2022 to 2025. The exposure was intent to use HCL using non\u2010pregnancy algorithms versus SAPT (reference) at the start of pregnancy. Outcomes included pregnancy outcomes (cesarean delivery, preeclampsia, preterm birth, small\u2010 and large\u2010for\u2010gestational\u2010age, neonatal intensive care unit admission, neonatal hypoglycemia, neonatal hyperbilirubinemia, and respiratory distress syndrome) and glycemic measures the week before delivery (hemoglobin A1c and continuous glucose monitor metrics including time in range within a pregnancy\u2010specific range [63\u2013140\u00a0mg\/dL], time above and below range, standard deviation, and mean glucose). An Inverse\u2010Probability\u2010of\u2010Treatment Weighting analytic approach was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 154 women with T1D, 68.2% intended to use HCL and 31.8% SAPT when initiating prenatal care (median gestational age of 8.0\u00a0weeks [interquartile range {IQR}, 7.3, 9.3]). In adjusted analyses, women using HCL had neonates with a higher birthweight (3640\u00a0vs. 3430 g; adj. beta, 271.98; 95% CI, 0.31, 543.65) and mean sensor glucose the week prior to delivery (150.0\u00a0vs. 145.0\u00a0mg\/dL; adj. beta, 13.36; 95% CI, 0.79, 25.93) and lower time below range compared with those using SAPT (2.0\u00a0vs. 4.0%; adj. beta, \u22123.73; 95% CI, \u22126.52, \u22120.93). Other pregnancy and glycemic outcomes did not differ between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Among a US cohort with T1D enrolled in a prenatal and diabetes care program, pregnancy and glycemic outcomes were similar between those using off\u2010label HCL versus SAPT. Evaluating how HCL with pregnancy\u2010specific algorithms can be used to promote maternal and child health could be most helpful for pregnant women with T1D and should be a research priority.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmf2.70392","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:01:32Z","timestamp":1788174092000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy and glycemic outcomes with hybrid closed\u2010loop insulin delivery versus sensor\u2010augmented pump therapy among women with type 1 diabetes"],"prefix":"10.1002","volume":"2","author":[{"given":"Annabeth","family":"Brewton","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radhika","family":"Pandit","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiqiang","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7860-6143","authenticated-orcid":false,"given":"Natasha","family":"Santhanam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellena","family":"Privitera","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaylyn","family":"Vickers","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Gabbe","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Grobman","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology Brown University  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark B.","family":"Landon","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8206-5235","authenticated-orcid":false,"given":"Christine P.","family":"Field","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6818-8925","authenticated-orcid":false,"given":"Elizabeth O.","family":"Buschur","sequence":"additional","affiliation":[{"name":"Division of Endocrinology Metabolism, and Diabetes Department of Medicine The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8043-556X","authenticated-orcid":false,"given":"Kartik K.","family":"Venkatesh","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(25)00335-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(24)00089-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602494"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2303911"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2025.10.015"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968251329288"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32400-5"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc23-0173"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcd.2025.11.006"}],"container-title":["Pregnancy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pmf2.70392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pmf2.70392","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pmf2.70392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:06:28Z","timestamp":1791529588000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pmf2.70392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/pmf2.70392"],"URL":"https:\/\/doi.org\/10.1002\/pmf2.70392","archive":["Portico"],"relation":{},"ISSN":["2997-9684","2997-9684"],"issn-type":[{"value":"2997-9684","type":"print"},{"value":"2997-9684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"2026-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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