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This paper and the others in this series address some aspects of this multifaceted validation paradigm, which requires that a disorder has a known clinical presentation, can be delimited from other disorders, \u2018runs\u2019 in families, and something of its aetiology, treatment response and course is known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three groups of subjects were studied: 104 adolescent inpatients meeting the Revised Diagnostic Interview for Borderlines and DSM\u2010IV criteria for BPD, 60 psychiatrically healthy adolescents and 290 adult inpatients meeting the Revised Diagnostic Interview for Borderlines and DSM\u2010III\u2010R criteria for BPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adolescents with BPD had significantly higher prevalence rates of 22 of the 24 symptoms studied than psychiatrically healthy adolescents. Only rates of serious treatment regressions and countertransference problems failed to reach the Bonferroni\u2010corrected level of 0.002. Adolescents and adults with BPD had only four symptomatic differences that reached this level of significance, with adolescents with BPD reporting significantly lower levels of quasi\u2010psychotic thought, dependency\/masochism, devaluation\/manipulation\/sadism and countertransference problems than adults with BPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Taken together, the results of this study suggest that adolescents report BPD as severe as that reported by adults. They also suggest that BPD in adolescents is not a tumultuous phase of normal adolescence. Copyright \u00a9 2017 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pmh.1378","type":"journal-article","created":{"date-parts":[[2017,5,29]],"date-time":"2017-05-29T04:22:42Z","timestamp":1496031762000},"page":"150-156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Prevalence rates of borderline symptoms reported by adolescent inpatients with BPD, psychiatrically healthy adolescents and adult inpatients with BPD"],"prefix":"10.1002","volume":"11","author":[{"given":"Mary C.","family":"Zanarini","sequence":"first","affiliation":[{"name":"McLean Hospital  Belmont MA USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina M.","family":"Temes","sequence":"additional","affiliation":[{"name":"McLean Hospital  Belmont MA USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1479-8733","authenticated-orcid":false,"given":"Laura R.","family":"Magni","sequence":"additional","affiliation":[{"name":"Unit of Psychiatry St. John of God Clinical Research Centre  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garrett M.","family":"Fitzmaurice","sequence":"additional","affiliation":[{"name":"McLean Hospital  Belmont MA USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blaise A.","family":"Aguirre","sequence":"additional","affiliation":[{"name":"McLean Hospital  Belmont MA USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Goodman","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai  New York NY USA"},{"name":"James J. 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