{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T03:07:46Z","timestamp":1779419266494,"version":"3.53.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Personality &amp;amp; Mental Health"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Adults with ADHD show substantial variability in response to pharmacological treatment, and comorbid personality pathology may help explain why symptom improvement often fails to translate into meaningful functional improvement. This naturalistic longitudinal study examined whether dimensional personality pathology predicts symptomatic and functional outcomes during routine stimulant treatment. A total of 246 adults with ADHD (66% women; mean age\u2009=\u200933.5) contributed repeated assessments over irregular follow\u2010up intervals, with substantial attrition across waves. Linear mixed\u2010effects models were used to accommodate unbalanced repeated measures. Linear mixed\u2010effects models indicated that higher personality dysfunction was strongly associated with less improvement in functioning (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2009=\u20090.44,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) and more persistent ADHD symptoms (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2009=\u20090.20,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), independent of stimulant dose and time in treatment. Negative affectivity, detachment, psychoticism, and disinhibition were the maladaptive trait domains most consistently linked to poorer functional outcomes, whereas disinhibition showed the strongest association with residual ADHD symptom burden. Medication\u2010related effects were modest in comparison. These findings identify personality pathology as a clinically relevant source of heterogeneity in adult ADHD treatment response and support routine assessment of personality functioning to inform clinical decision\u2010making.\n                  <\/jats:p>","DOI":"10.1002\/pmh.70071","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T05:19:39Z","timestamp":1774847979000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Personality Pathology and Functional Outcomes During Pharmacological Treatment of Adult ADHD"],"prefix":"10.1002","volume":"20","author":[{"given":"Peter","family":"Jacobsson","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg  Sweden"},{"name":"Psychiatry Halland, Region Halland  Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin","family":"Palage","sequence":"additional","affiliation":[{"name":"Psychiatry Halland, Region Halland  Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-8645","authenticated-orcid":false,"given":"Christopher\u00a0J.","family":"Hopwood","sequence":"additional","affiliation":[{"name":"University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"S\u00f6derpalm","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg  Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9127-5509","authenticated-orcid":false,"given":"Robert\u00a0F.","family":"Krueger","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Tasselius","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Medicine, Institute of Medicine, the Sahlgrenska Academy University of Gothenburg  Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Centre for Ethics, Law and Mental Health (CELAM), Institute of Neuroscience and Physiology University of Gothenburg  Gothenburg Sweden"},{"name":"Forensic Psychiatry Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,29]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM\u20105","author":"APA","year":"2013"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2023.115449"},{"key":"e_1_2_11_4_1","volume-title":"Attention\u2010Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment","author":"Barkley R. 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