{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:44:33Z","timestamp":1790837073783,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T00:00:00Z","timestamp":1661212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Proteomics"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The recent and sudden outbreak of monkeypox in numerous non\u2010endemic countries requires expanding its surveillance immediately and understanding its origin and spread. As learned from the COVID\u201019 pandemic, appropriate detection techniques are crucial to achieving such a goal. Mass spectrometry has the advantages of a rapid response, low analytical interferences, better precision, and easier multiplexing to detect various pathogens and their variants. In this proteomic dataset, we report experimental data on the proteome of the monkeypox virus (MPXV) recorded by state\u2010of\u2010the\u2010art shotgun proteomics, including data\u2010dependent and data\u2010independent acquisition for comprehensive coverage. We highlighted 152 viral proteins, corresponding to an overall proteome coverage of 79.5 %. Among the 1371 viral peptides detected, 35 peptides with the most intense signals in mass spectrometry were selected, representing a subset of 13 viral proteins. Their relevance as potential candidate markers for virus detection by targeted mass spectrometry is discussed. This report should assist the rapid development of mass spectrometry\u2010based tests to detect a pathogen of increasing concern.<\/jats:p>","DOI":"10.1002\/pmic.202200253","type":"journal-article","created":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T11:13:26Z","timestamp":1660562006000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Mass spectrometry detection of monkeypox virus: Comprehensive coverage for ranking the most responsive peptide markers"],"prefix":"10.1002","volume":"23","author":[{"given":"Cl\u00e9ment","family":"Lozano","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Grenga","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Gallais","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guylaine","family":"Miotello","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Bellanger","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1589-445X","authenticated-orcid":false,"given":"Jean","family":"Armengaud","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay CEA, INRAE, D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS), SPI  Bagnols\u2010sur\u2010C\u00e8ze France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,23]]},"reference":[{"issue":"2","key":"e_1_2_6_2_1","first-page":"165","article-title":"Human monkeypox, 1970\u201379","volume":"58","author":"Breman J. 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