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It was hypothesized that there would be heterogeneity in post\u2010PRP protocols.<\/jats:p><\/jats:sec><jats:sec><jats:title>Literature Survey<\/jats:title><jats:p>A systematized review of the literature on post\u2010PRP protocols for tendinopathy was conducted using an electronic search of MEDLINE and Embase databases through September 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>After duplicates were removed, English language articles involving adult patients who received PRP for tendinopathy were reviewed. Exclusion criteria included studies with fewer than 10 patients, PRP used to treat pathology other than tendinopathy, multiple protocols in one study, and surgical settings. Protocol specifics were extracted including nonsteroidal anti\u2010inflammatory drugs (NSAID) restrictions before and after injection, postinjection restrictions on movement and weight bearing, use of orthoses, activity modifications, and postinjection rehabilitation protocols. Given limitations in the data, a meta\u2010analysis was not performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Synthesis<\/jats:title><jats:p>Eighty\u2010four studies met inclusion criteria. Following PRP injection, weight\u2010bearing restrictions were mentioned rarely (12% of protocols). Orthosis use was uncommon overall (18%) but more common in Achilles tendinopathy protocols (53%). The majority of protocols instituted a period of stretching (51%) and strengthening (54%). Stretching programs generally began 2\u20107 days following injection, and strengthening programs began within 2\u20103 weeks. Preinjection NSAID restriction was reported rarely (20%), whereas postinjection NSAID restriction was more common (56%), with a typical restriction of greater than 2 weeks (38%). Return to play or full activity was reported in 42% of protocols, most commonly at 4\u20106 weeks following injection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although the clinical effectiveness of PRP remains controversial, even less is known about the effect of post\u2010PRP protocols, which may affect the outcomes attributed to PRP itself. No studies directly compare post\u2010PRP protocols, and the protocols studied demonstrate substantial heterogeneity. 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