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But there is limited evidence for its safety and feasibility in people with stroke with varying impairment levels in the early subacute phase of stroke recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the safety and feasibility of cardiorespiratory fitness testing in the early subacute phase after stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A sub\u2010study of a larger single service, multi\u2010site, prospective cohort feasibility study (Cardiac Rehabilitation in Stroke Survivors to Improve Survivorship [CRiSSIS]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Private subacute inpatient rehabilitation facilities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Consecutive admissions of people with ischemic stroke admitted to subacute rehabilitation facilities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>Not applicable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome(s)<\/jats:title><jats:p>Safety was determined by the occurrence of adverse or serious adverse events. Feasibility was determined by assessing the (1) number of participants recruited and (2) number of participants able to complete the fitness test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between April 2018 and December 2019, a total of 165 people with stroke were screened to participate; 109 were eligible and 65 were recruited. Of the 62 who completed testing, 41 participants were able to complete a submaximal fitness test at a median of 12\u2009days post\u2010stroke. One minor adverse event was recorded. Of the 21 participants unable to complete the fitness test; 4 declined to complete the test, 9 were unable to commence the test, and 8 were unable to complete the first stage of the protocol due to stroke\u2010related impairments. Participants with mild stroke, greater motor and cognitive function, and fewer depressive symptoms were more likely to be able to complete the cardiorespiratory fitness test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cardiorespiratory fitness testing was safe for most people with mild\u2010to\u2010moderately severe ischemic stroke and transient ischemic attack in the early subacute phase, but only two\u2010thirds of the participants could complete the test.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pmrj.12787","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T12:15:06Z","timestamp":1644840906000},"page":"291-301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The safety and feasibility of early cardiorespiratory fitness testing after stroke"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8841-8561","authenticated-orcid":false,"given":"Natasha","family":"Machado","sequence":"first","affiliation":[{"name":"Rehabilitation, Epworth Healthcare  89 Bridge Road Richmond Victoria"},{"name":"Physiotherapy Department, Faculty of Medicine, Dentistry and Health Science University of Melbourne  Parkville Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2758-7473","authenticated-orcid":false,"given":"Gavin","family":"Williams","sequence":"additional","affiliation":[{"name":"Rehabilitation, Epworth Healthcare  89 Bridge Road Richmond Victoria"},{"name":"Physiotherapy Department, Faculty of Medicine, Dentistry and Health Science University of Melbourne  Parkville Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7069-1191","authenticated-orcid":false,"given":"John","family":"Olver","sequence":"additional","affiliation":[{"name":"Rehabilitation, Epworth Healthcare  89 Bridge Road Richmond Victoria"},{"name":"Physiotherapy Department, Faculty of Medicine, Dentistry and Health Science University of Melbourne  Parkville Victoria"},{"name":"Department of Medicine Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4916-049X","authenticated-orcid":false,"given":"Liam","family":"Johnson","sequence":"additional","affiliation":[{"name":"Rehabilitation, Epworth Healthcare  89 Bridge Road Richmond Victoria"},{"name":"Physiotherapy Department, Faculty of Medicine, Dentistry and Health Science University of Melbourne  Parkville Victoria"},{"name":"Faculty of Exercise Science Australian Catholic University  Fitzroy Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000022"},{"key":"e_1_2_8_3_1","unstructured":"Stroke Foundation.Clinical Guidelines for Stroke Management. 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