{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T04:07:44Z","timestamp":1773374864154,"version":"3.50.1"},"reference-count":64,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prosthetic socket coupling with the residual limb should be comfortable without causing skin breakdown or excessive pressure. However, users report socket discomfort, and there is a scarcity of objective measurements available to assess this feeling of discomfort. Quantifying the specific pressure may enable clinicians and users to determine and improve comfort levels objectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>(1) To evaluate if a peak pressure reduction assists in resolving wounds, redness, and pain inside prosthetic sockets in people with transtibial amputation. (2) To determine if peak pressures measured inside the prosthetic socket due to external forces could be used to quantify the level of improvement in socket discomfort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>In this cohort study, we used a pressure sensor to quantify and facilitate adjustments to the prosthetic socket, correlating this information to the user\u02bcs socket comfort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Outpatient clinic in a tertiary hospital in Singapore.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>People (<jats:italic>N<\/jats:italic>\u00a0=\u00a016) with unilateral transtibial lower limb amputation using a prosthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>NA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Peak pressure and socket comfort score (SCS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The peak pressure value showed a statistically significant reduction across all participants following adjustments at a 50% delta change in pressure (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.001). This was achieved with a mean number of 2.6\u2009\u00b1\u20091.4 adjustments per participant. Following the adjustments, the paired <jats:italic>t<\/jats:italic>\u2010test results showed a mean increase between the first SCS and final SCS was 2.6 (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The wound, redness, and pain resolved in 15 of 16 participants regardless of diabetic status following socket adjustments. Although the peak pressures values did not correlate to the SCS score, the reduction in peak pressure saw significant improvement to the SCS. The use of a portable sensor is a fast and efficient means to quantify adjustments inside the prosthetic socket and could potentially be considered as part of future care delivery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pmrj.12796","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T05:04:10Z","timestamp":1646197450000},"page":"482-492","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Measuring discomfort\u2014An objective method for quantifying peak pressure discomfort and improved fit in adults with transtibial amputation"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5385-0354","authenticated-orcid":false,"given":"Trevor","family":"Binedell","sequence":"first","affiliation":[{"name":"Prosthetics and Orthotics Department Tan Tock Seng Hospital  Singapore Singapore"},{"name":"Engineering Product Development Singapore University of Technology 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