{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:00:39Z","timestamp":1787792439512,"version":"build-2784847793"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Neuromuscular ultrasound plays an increasing role in diagnosing carpal tunnel syndrome (CTS). There are limited data supporting the correlation between the electrodiagnostic studies and ultrasound measurements in CTS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the association between different electrodiagnostic severities and ultrasound measurements of the median nerve in CTS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>An academic tertiary care center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>Patients 18 years or older evaluated with upper limb electrodiagnostic studies and neuromuscular ultrasound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measurement<\/jats:title><jats:p>Ultrasound measurements of the median nerve cross\u2010sectional area (CSA) at the wrist and the calculated wrist\u2010to\u2010forearm ratio (WFR) were compared with the electrodiagnostic severity (normal, mild, moderate, and severe). Mean analysis and analysis of variance test (<jats:italic>\u03b1<\/jats:italic>\u2009=\u20090.05) were performed to assess the association.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1359 limbs were identified. There was a statistically significant association between electrodiagnostic severity of CTS and median nerve CSA at the wrist (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), as well as the WFR (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The mean median nerve CSA at the wrist and WFR were 7.01\u2009\u00b1\u20092.06\u2009mm<jats:sup>2<\/jats:sup> (95% CI: 6.80\u20137.20) and 1.24\u2009\u00b1\u20090.36 (95% CI: 1.16\u20131.24) in electrodiagnostically normal median nerves, 10.47\u2009\u00b1\u20092.82\u2009mm<jats:sup>2<\/jats:sup> (95% CI: 10.25\u201310.75) and 2.06\u2009\u00b1\u20090.67 (95% CI: 2.04\u20132.16) in electrodiagnostically mild CTS, 12.95\u2009\u00b1\u20094.74\u2009mm<jats:sup>2<\/jats:sup> (95% CI: 12.41\u201313.59) and 2.49\u2009\u00b1\u20091.04 (95% CI: 2.37, 2.63) in electrodiagnostically moderate CTS, and 14.69\u2009\u00b1\u20095.38\u2009mm<jats:sup>2<\/jats:sup> (95% CI: 13.95\u201315.44) and 2.71\u2009\u00b1\u20091.02 (95% CI: 2.56\u20132.84) in electrodiagnostically severe CTS, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests a direct association between electrodiagnostic severity and ultrasound measurements of the median nerve in patients with suspected CTS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pmrj.13168","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T10:30:06Z","timestamp":1711449006000},"page":"1191-1195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between electrodiagnosis and neuromuscular ultrasound in the diagnosis and assessment of severity of carpal tunnel syndrome"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1417-1906","authenticated-orcid":false,"given":"Soun","family":"Sheen","sequence":"first","affiliation":[{"name":"Department of PM&amp;R University of Rochester  Rochester New York USA"},{"name":"Department of Pain Medicine MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aabra","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Rochester  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattie E.","family":"Raiford","sequence":"additional","affiliation":[{"name":"Department of Orthopedics University of Rochester  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney M. 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